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Clinical trialNCT06051409RecruitingPhase 3Interventional

A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)

SponsorAscentage Pharma Group Inc.Enrollment350Leukemia, Lymphoblastic, Acute, Philadelphia-PositivePh+ ALL
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

90 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Royal North Shore Hospital

    St Leonards, New South Wales, Australia

    Active, not recruiting
  • Royal Adelaide Hospital

    Adelaide, South Australia, Australia

    Active, not recruiting
  • Alfred Health

    Melbourne, Victoria, Australia

    Active, not recruiting
  • Royal Perth Hospital

    Perth, Washington, Australia

    Active, not recruiting
China
  • the First Affiliated Hospital of Bengbu Medical School

    Bengbu, Anhui, China

    Yanli Yang, M.D.
    Not, yet, recruiting
  • Xinqiao Hospital of Army Medical University

    Chongqing, Chongqing Municipality, China

    Cheng Zhang, M.D.
    Recruiting
  • Guangdong Province People'S Hospital

    Guangdong, Guangzhou, China

    Jianyu Weng, M.D.
    Recruiting
  • Nanfang Hospital of Southern Medical University

    Guangdong, Guangzhou, China

    Hongsheng Zhou, M.D.
    Recruiting
  • Henan Cancer Hospital

    Zhengzhou, Henan, China

    Xudong Wei, M.D.
    Recruiting
  • Wuhan Union Hospital of Tongji Medical College of Huazhong University of Science and Technology

    Wuhan, Hubei, China

    Mei Hong, M.D.
    Recruiting
  • the First Affiliated Hospital of Suzhou University

    Suzhou, Jiangsu, China

    Suning Chen, M.D.,Ph.D.
    Recruiting
  • Shanghai Jiao Tong University School of Medicine Ruijin Hospital

    Shanghai, Shanghai Municipality, China

    Weili Zhao, M.D.,Ph.D.
    Not, yet, recruiting
  • West China Hospital of Sichuan University

    Chengdu, Sichuan, China

    Yu Wu, M.D.
    Recruiting
  • Institute of Blood Transfusion of Chinese Academy of Medical Sciences

    Tianjin, Tianjin Municipality, China

    Ying Wang, M.D.
    Recruiting
Czechia
  • Ascentage Investigative Site #8647

    Brno, Czechia

    Not, yet, recruiting
  • Ascentage Investigative Site #6305

    Hradec Králové, Czechia

    Not, yet, recruiting
  • Ascentage Investigative Site #6304

    Ostrava, Czechia

    Not, yet, recruiting
  • Ascentage Investigative Site #6302

    Prague, Czechia

    Not, yet, recruiting
  • Ascentage Investigative Site #6309

    Prague, Czechia

    Not, yet, recruiting
France
  • Ascentage Investigative Site #5020

    Le Chesnay, France

    Not, yet, recruiting
  • Ascentage Investigative Site #5021

    Lyon, France

    Not, yet, recruiting
  • Ascentage Investigative Site #5013

    Nantes, France

    Not, yet, recruiting
  • Ascentage Investigative Site #5025

    Nice, France

    Not, yet, recruiting
  • Ascentage Investigative Site #5019

    Pessac, France

    Not, yet, recruiting
  • Ascentage Investigative Site #5024

    Pierre-Bénite, France

    Not, yet, recruiting
  • Ascentage Investigative Site #5022

    Poitiers, France

    Not, yet, recruiting
  • Ascentage Investigative Site #5018

    Toulouse, France

    Not, yet, recruiting
Italy
  • Ascentage Investigative Site #5538

    Bologna, Italy

    Not, yet, recruiting
  • Ascentage Investigative Site #5529

    Meldola, Italy

    Not, yet, recruiting
  • Ascentage Investigative Site #5539

    Milan, Italy

    Not, yet, recruiting
  • Ascentage Investigative Site #5533

    Monza, Italy

    Not, yet, recruiting
  • Ascentage Investigative Site #5540

    Ravenna, Italy

    Not, yet, recruiting
  • Ascentage Investigative Site #5531

    Roma, Italy

    Not, yet, recruiting
  • Ascentage Investigative Site #5550

    Torino, Italy

    Not, yet, recruiting
  • Ascentage Investigative Site #5536

    Varese, Italy

    Not, yet, recruiting
Romania
  • Ascentage Investigative Site #6503

    Bucharest, Romania

    Not, yet, recruiting
  • Ascentage Investigative Site #6502

    Cluj-Napoca, Romania

    Not, yet, recruiting
  • Ascentage Investigative Site #6507

    Craiova, Romania

    Not, yet, recruiting
  • Ascentage Investigative Site #6504

    Iași, Romania

    Not, yet, recruiting
Singapore
  • Ascentage Investigative Site #6602

    Singapore, Singapore

    Not, yet, recruiting
50 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Investigator's choice of TKIOlverembatinib
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Aug 2023
Primary completion
31 Dec 2027
Completion
30 Jun 2029
Last update posted
30 Apr 2026
Registered enrollment
350
Registry id
NCT06051409

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.