Clinical trialNCT06055608RecruitingPhase 2Interventional

Advancing Transplantation Outcomes in Children

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment200Kidney Transplant

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a pediatric kidney transplant study comparing the safety and efficacy of an immunosuppressive regimen of belatacept and sirolimus to tacrolimus and Mycophenolate Mofetil (MMF). Two hundred participants will be randomized (1:1) to one of two groups within 24 hours following the transplant procedure. The duration of the study from time of transplant to the primary endpoint is 12-24 months.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

David Briscoe, MD
Boston Children's Hospital: Pediatric Transplantation
Study Chair
clinicaltrials.gov ↗
Eileen Chambers, MD
Duke University Medical Center: Department of Pediatrics
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

20 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham (site # 71038)
Birmingham, Alabama, United States
Recruiting
Cedars-Sinai Medical Center (site #: 71026)
Los Angeles, California, United States
Recruiting
Children'S Hospital of Los Angeles (site #: 71036)
Los Angeles, California, United States
Not, yet, recruiting
Mattel Children'S Hospital, Ucla (site #: 71012)
Los Angeles, California, United States
Recruiting
Ucsd Rady Children'S Hospital (site #: 71037)
San Diego, California, United States
Recruiting
Children'S Hospital of Colorado (site #: 71019)
Aurora, Colorado, United States
Recruiting
Nemours Children'S Health (site #: 71042)
Wilmington, Delaware, United States
Recruiting
Children'S National Medical Center (site #: 71039)
Washington D.C., District of Columbia, United States
Recruiting
Ann and Robert H. Lurie Children'S Hospital of Chicago (site #: 71016)
Chicago, Illinois, United States
Recruiting
Johns Hopkins Children'S Center (site #: 71025)
Baltimore, Maryland, United States
Recruiting
Boston Children'S Hospital (site #: 71001)
Boston, Massachusetts, United States
Recruiting
Helen Devos Children'S Hospital (site #: 71035)
Grand Rapids, Michigan, United States
Recruiting
Washington University/st. Louis Children'S Hospital (site #: 71006)
St Louis, Missouri, United States
Recruiting
New York Medical College/boston Children'S Health Physicians
Westchester, New York, United States
Not, yet, recruiting
Duke University (site #: 71033)
Durham, North Carolina, United States
Recruiting
Cincinnati Children'S Hospital Medical Center (site #: 71017)
Cincinnati, Ohio, United States
Recruiting
Children'S Hospital of Philadelphia (site #: 71091)
Philadelphia, Pennsylvania, United States
Recruiting
Upmc Children'S Hospital of Pittsburgh (site #: 71008)
Pittsburgh, Pennsylvania, United States
Recruiting
Texas Children'S Hospital (baylor) (site #: 71005)
Houston, Texas, United States
Recruiting
Seattle Children'S Hospital (site #: 71041)
Seattle, Washington, United States
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Lymphocyte immune globulin, anti-thymocyte globulin →Belatacept →Mycophenolate mofetil →Sirolimus →Tacrolimus →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 22 May 2024
Primary completion: 30 Jun 2028
Completion: 30 Jun 2028
Last update posted: 20 May 2026
Registered enrollment: 200
Registry id: NCT06055608

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.