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Clinical trialNCT06086704RecruitingPhase 2Interventional

Study of 18F-FFNP Breast PET/MRI

SponsorUniversity of Wisconsin, MadisonEnrollment53Breast Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This clinical trial will investigate an estrogen-regulated parameter as an early measure of endocrine therapy response: progesterone receptor (PR) protein with a progestin-based radioligand, 18F-fluorofuranylnorprogesterone (18F-FFNP). The overall purpose of this research is to test the efficacy of 18F-FFNP PET/MRI for predicting response to presurgical endocrine therapy and to determine the quantitative reliability of 18F-FFNP breast PET/MRI in patients with newly diagnosed PR+ primary breast cancer.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Uw Carbone Cancer Center

    Madison, Wisconsin, United States

    Aparna M Mahajan, MDEmmanuel Sampene, PhDKari B Wisinski, MDLee G Wilke, MDLonie R Salkowski, MD, MS, PhDRoberta M Strigel, MD, MSScott B Perlman, MDStephanie M McGregor, MD, PhD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Fluorofuranylnorprogesterone F-18Anastrozole →FDA-approved gadolinium-based intravenous contrast agent
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
25 Sept 2024
Primary completion
31 Jan 2027
Completion
31 Jan 2030
Last update posted
18 May 2026
Registered enrollment
53
Registry id
NCT06086704
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.