Clinical trialNCT06087029RecruitingInterventional

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

SponsorDuke UniversityEnrollment1,100Type B Aortic Dissection

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this clinical trial is to determine whether an upfront invasive strategy of TEVAR plus medical therapy reduces the occurrence of a composite endpoint of all-cause death or major aortic complications compared to an upfront conservative strategy of medical therapy with surveillance for deterioration in patients with uncomplicated type B aortic dissection.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Firas F Mussa, M.D.
The University of Texas at Houston
Principal Investigator
clinicaltrials.gov ↗
Manesh R Patel, M.D.
Duke University
Principal Investigator
clinicaltrials.gov ↗
Panos Kougias, M.D.
The State University of New York at Downstate
Principal Investigator
clinicaltrials.gov ↗
Sean O'Brien, Ph.D.
Duke University
Principal Investigator
clinicaltrials.gov ↗
Sreekanth Vemulapalli, M.D.
Duke University
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

63 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Chum - Centre Hospitalier de L'Universite de Montreal
Montreal, Quebec, Canada
Laura Drudi, MD
Recruiting
Mcgill University Medical Center
Montreal, Quebec, Canada
Robert James Doonan, MD
Recruiting

United States

University of Alabama at Birmingham
Birmingham, Alabama, United States
Adam Beck, MD
Recruiting
Honorhealth
Phoenix, Arizona, United States
Hasan Aldailami, MD
Recruiting
Memorial Care Long Beach Medical Center
Long Beach, California, United States
Rodney White, MD
Recruiting
Keck Medical Center of Usc
Los Angeles, California, United States
Alyssa Pyun, MD
Recruiting
University of California San Diego
San Diego, California, United States
Withdrawn
University of California
San Francisco, California, United States
Jade Hiramoto, MD
Recruiting
Stanford University Medical Center
Stanford, California, United States
Withdrawn
University of Colorado Denver
Aurora, Colorado, United States
Brett Reece
Recruiting
Memorial Hospital Central
Colorado Springs, Colorado, United States
Mel Sharafuddin, MD
Recruiting
Hartford Hospital
Hartford, Connecticut, United States
Mohiuddin Cheema, MD
Recruiting
Yale University
New Haven, Connecticut, United States
David Kuwayama, MD
Recruiting
University of Florida Health
Gainesville, Florida, United States
Michol Cooper, MD
Recruiting
Tampa General Hospital
Tampa, Florida, United States
Halim Yammine, MD
Recruiting
Northwestern University
Chicago, Illinois, United States
Mark Eskandari, MD
Recruiting
the University of Chicago
Chicago, Illinois, United States
Withdrawn
Southern Illinois University School of Medicine
Springfield, Illinois, United States
Laura Healy, MD
Recruiting
Indiana University Methodist Hospital
Indianapolis, Indiana, United States
Raghu Motaganahalli, MD
Recruiting
University of Kansas Medical Center
Kansas City, Kansas, United States
William Poulson, MD
Recruiting
Mainehealth
Scarborough, Maine, United States
Kristina Giles, MD
Recruiting
Johns Hopkins University
Baltimore, Maryland, United States
Caitlin Hicks, MD
Recruiting
Brigham and Women'S Hospital
Boston, Massachusetts, United States
Matthew T Menard, MD
Recruiting
Massachusetts General Hospital
Boston, Massachusetts, United States
Matthew Eagleton, MD
Recruiting
University of Massachusetts Memorial
Worcester, Massachusetts, United States
Andres Schanzer, MD
Recruiting
University of Michigan Health
Ann Arbor, Michigan, United States
Bo Yang, MD
Recruiting
Henry Ford Health System
Detroit, Michigan, United States
Loay Kabbani, MD
Recruiting
Spectrum Health and Hospitals and Corewell
Grand Rapids, Michigan, United States
Eanas Yassa, MD
Recruiting
University of Minnesota
Minneapolis, Minnesota, United States
Nolan Cirillo-Penn, MD
Recruiting
Mayo Clinic
Rochester, Minnesota, United States
Withdrawn
University of Missouri Health Care
Columbia, Missouri, United States
Jonathan Bath, MD
Recruiting
Washington University School of Medicine
St Louis, Missouri, United States
Withdrawn
University of Nebraska Medical Center
Omaha, Nebraska, United States
Withdrawn
Cooper University Hospital
Camden, New Jersey, United States
Philip Batista, MD
Recruiting
Rutgers Uh Vascular Center
Jersey City, New Jersey, United States
Karim Salem, MD
Recruiting
Maimonides Medical Center
Brooklyn, New York, United States
Withdrawn
Icahn School of Medicine at Mount Sinai
New York, New York, United States
Rami Tadros, MD
Recruiting
Nyu Langone Health
New York, New York, United States
Gregory Magee, MD
Recruiting
University of Rochester Medical Center
Rochester, New York, United States
Doran Mix, MD
Recruiting
St. Francis Hospital and Heart Center
Roslyn, New York, United States
Timothy Carter, MD
Recruiting

23 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 14 Apr 2024
Primary completion: 1 Jun 2030
Completion: 30 Jun 2030
Last update posted: 29 Apr 2026
Registered enrollment: 1,100
Registry id: NCT06087029

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.