FindMyKOL
Clinical trialNCT06153173RecruitingPhase 2Interventional

Mirdametinib in Histiocytic Disorders

SponsorChildren's Hospital Medical Center, CincinnatiEnrollment40Histiocytic DisordersJuvenile Xanthogranuloma (JXG)Langerhans Cell Histiocytosis (LCH)Rosai-Dorfman Disease (RDD)
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to see if treatment with mirdametinib in patients with Langerhans cell histiocytosis (LCH) or other histiocytic disorders will be better than current treatments and with fewer side effects.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

  • Allison Bartlett, MD

    Children's Hospital Medical Center, Cincinnati

    Principal Investigator
    clinicaltrials.gov ↗
  • Ashish Kumar, MD, PhD

    Children's Hospital Medical Center, Cincinnati

    Principal Investigator
    clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Cincinnati Children'S Hospital Medical Center

    Cincinnati, Ohio, United States

    Ashish Kumar, MD, PhD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Mirdametinib →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
5 Feb 2024
Primary completion
31 Mar 2030
Completion
31 Mar 2031
Last update posted
16 Sept 2025
Registered enrollment
40
Registry id
NCT06153173
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.