Clinical trialNCT06173544CompletedInterventional

HIV Engagement and Adolescent Depression Support (HEADS-UP)

SponsorUniversity of North Carolina, Chapel HillEnrollment106Adolescent BehaviorAnxietyDepressionHIV InfectionsImmune System Diseases

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This pilot study will individually randomize 105 adolescents living with HIV 1:1:1 to standard of care, adapted intervention, or enhanced intervention. The intervention is called the Friendship Bench Intervention is a counseling intervention for depression and engagement in HIV care.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Bradley N Gaynes, MD
University of North Carolina, Chapel Hill
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Nivedita L Bhushan, PhD
RTI International
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Malawi

Area 18 Health Centre
Lilongwe, Malawi
Area 25 Health Centre
Lilongwe, Malawi
Kawale Health Centre
Lilongwe, Malawi
Lighthouse Health Centre
Lilongwe, Malawi
Unc Project Malawi
Lilongwe, Malawi

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 6 Jul 2024
Primary completion: 22 Oct 2025
Completion: 22 Oct 2025
Last update posted: 16 Jul 2026
Registered enrollment: 106
Registry id: NCT06173544

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.