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Clinical trialNCT06193200CompletedPhase 3Interventional

Evaluate the Neurological Effects of EryDex on Subjects With A-T

SponsorQuince Therapeutics S.p.A.Enrollment105Ataxia Telangiectasia
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is an international, multi-center, randomized, prospective, double-blind, placebo-controlled, Phase 3 study, designed to assess the effect of EryDex (dexamethasone sodium phosphate \[DSP\] in autologous erythrocytes), administered by intravenous (IV) infusion once every 28 days, on neurological symptoms of patients with Ataxia Telangiectasia (A-T).

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

19 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Denmark
  • Copenhagen University Hospital, Rigshospitalet, Department of Pediatric Neurology

    Copenhagen, Denmark

Germany
  • Ikf Pneumologie Gmbh & Co. Kg; Institut Für Klinische Forschung Pneumologie Clinical Research Center Respiratory Diseases

    Frankfurt, Germany

  • University Hospital Frankfurt, Pediatric and Adolescent Clinic

    Frankfurt, Germany

Italy
  • Spedali Civili Di Brescia, Pediatric Immunology Department

    Brescia, Italy

  • Policlinico Umberto I, la Sapienza University, Department of Neurosciences and Menthal Health

    Roma, Italy

Norway
  • Oslo University Hospital, Rikshospitalet, Division of Pediatric and Adolescent Medicine, Norwegian National Unit for Newborn Screening

    Oslo, Norway

Poland
  • Medpolonia Sp Zoo

    Poznan, Poland

  • Instytut "pomnik-Centrum Zdrowia Dziecka", Immunology Clinic

    Warsaw, Poland

Spain
  • Hospital Universitari Vall D'Hebron, Department of Pediatric Neurology

    Barcelona, Spain

  • Hospital Universitario la Paz, Department of Pediatric Neurology

    Madrid, Spain

Switzerland
  • University Children'S Hospital Zürich - Eleonore Foundation

    Zurich, Switzerland

United Kingdom
  • University Hospitals Birmingham Nhs Foundation Trust

    Birmingham, United Kingdom

  • Great Ormond Street Hospital for Children, Zayed Centre for Research

    London, United Kingdom

  • St George'S University Hospitals Nhs Foundation Trust, Centre for Neonatal and Paediatric Infection

    London, United Kingdom

  • Nottingham Children'S Hospital, Queen'S Medical Center, Children'S Neurology

    Nottingham, United Kingdom

United States
  • University of California Los Angeles (ucla), Ataxia Center and Hd Center of Excellence

    Los Angeles, California, United States

  • the Johns Hopkins Hospital, Division of Pediatric Allergy and Immunology

    Baltimore, Maryland, United States

  • Cincinnati Children'S Hospital, Division of Neurology

    Cincinnati, Ohio, United States

  • Ut Health Houston, Department of Pediatrics, Division of Child & Adolescent Neurology

    Houston, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
24 Jun 2024
Primary completion
17 Dec 2025
Completion
17 Dec 2025
Last update posted
30 Apr 2026
Registered enrollment
105
Registry id
NCT06193200

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.