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Clinical trialNCT06274047RecruitingPhase 3Interventional

PROSTATE-IQ: Parallel RandOmized STudy of Personalized Apalutamide Treatment and Evaluation to Improve Quality of Life in Post-Operative Radiation With Androgen Axis Suppression. A Phase III Multi-center Study for Men With Detectable PSA After Prostatectomy for Prostate Cancer.

SponsorM.D. Anderson Cancer CenterEnrollment120Androgen Axis SuppressionProstate CancerProstatectomy
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

1. Personalize treatment for prostate cancer based on how aggressive the disease is and 2. Learn if apalutamide-based treatment can help to reduce fatigue and other side effects of treatment in participants who are being treated with radiation therapy for prostate cancer, as compared to standard therapy.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Banner Md Anderson

    Gilbert, Arizona, United States

    Yerko Borghero, MD
    Recruiting
  • Rush Md Anderson

    Chicago, Illinois, United States

    Dian Wang, MD
    Recruiting
  • University of Kansas Medical Center

    Kansas City, Kansas, United States

    Xinglei Shen, MD
    Recruiting
  • Dana-Farber Cancer Institute

    Boston, Massachusetts, United States

    Paul Nguyen, MD
    Recruiting
  • Memorial Sloan Kettering Cancer Center

    New York, New York, United States

    Marisa Kollmeier, MD
    Recruiting
  • Md Anderson Cancer Center

    Houston, Texas, United States

    Karen Hoffman, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Androgen deprivation therapy →Apalutamide →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
10 Sept 2024
Primary completion
30 Jun 2027
Completion
30 Jun 2029
Last update posted
22 Jul 2026
Registered enrollment
120
Registry id
NCT06274047
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.