Clinical trialNCT06310031RecruitingInterventional

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

SponsorBrioHealth Solutions, Inc.Enrollment780Cardiovascular DiseasesHeart DiseasesHeart Failure

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this study is to evaluate the safety and efficacy of the BrioVAD System by demonstrating non-inferiority to the HeartMate 3 Left Ventricular Assist System when used for the treatment of advanced, refractory, left ventricular heart failure.

clinicaltrials.gov ↗

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

47 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham Hospital
Birmingham, Alabama, United States
Jose Tallaj, MD
Recruiting
Baptist Health Medical Center-Little Rock
Little Rock, Arkansas, United States
Recruiting
Cedars-Sinai Medical Center
Los Angeles, California, United States
Fardad Esmailian, MD
Recruiting
Uf Health Shands Hospital
Gainesville, Florida, United States
Recruiting
Advent Health
Orlando, Florida, United States
Andrija Vidic, MD
Recruiting
Emory University
Atlanta, Georgia, United States
Mani Daneshmand, MD
Recruiting
Piedmont Healthcare
Atlanta, Georgia, United States
Ezequiel Molina, MD
Recruiting
Advocate Christ Medical Center
Chicago, Illinois, United States
Antone Tatooles, MD
Recruiting
Northwestern University
Chicago, Illinois, United States
Recruiting
University of Chicago
Chicago, Illinois, United States
Recruiting
Ascension St. Vincent Hospital - Indianapolis
Indianapolis, Indiana, United States
Ashwin Ravichandran, MD
Recruiting
the University of Kansas Medical Center
Kansas City, Kansas, United States
Matthew Danter, MD
Recruiting
University of Kentucky
Lexington, Kentucky, United States
Emma Birks, MD
Recruiting
University of Louisville
Louisville, Kentucky, United States
Mark Slaughter
Recruiting
the Johns Hopkins Hospital
Baltimore, Maryland, United States
Ahmet Kilic, MD
Recruiting
University of Maryland Medical Center
Baltimore, Maryland, United States
Howard Massey
Recruiting
Massachusetts General Hospital
Boston, Massachusetts, United States
David D'Alessandro, MD
Recruiting
Tufts Medical Center
Boston, Massachusetts, United States
Gaurav Gulati
Recruiting
University of Michigan
Ann Arbor, Michigan, United States
Recruiting
Henry Ford Health
Detroit, Michigan, United States
Recruiting
Corewell Health Grand Rapids Hospital
Grand Rapids, Michigan, United States
Recruiting
Abbott Northwestern Hospital
Minneapolis, Minnesota, United States
Recruiting
University of Minnesota
Minneapolis, Minnesota, United States
Andrew Shaffer
Recruiting
Washu Medicine
St Louis, Missouri, United States
Amit Pawale
Recruiting
University of Nebraska Medical Center
Omaha, Nebraska, United States
Scott Lundgren
Recruiting
Newark Beth Israel Medical Center
Newark, New Jersey, United States
Igor Gosev, MD
Recruiting
Columbia University Irving Medical Center/ New York Presbyterian Hospital
New York, New York, United States
Koji Takeda
Recruiting
Mount Sinai
New York, New York, United States
Anelechi Anyanwu
Recruiting
Nyu Langone Health
New York, New York, United States
Marzia Leacche, MD
Recruiting
Weill Cornell Medicine
New York, New York, United States
Yoshifumi Naka, MD
Recruiting
Montefiore Medical Center
The Bronx, New York, United States
Daniel Goldstein, MD
Recruiting
Duke University
Durham, North Carolina, United States
Recruiting
the Christ Hospital - Cincinnati
Cincinnati, Ohio, United States
Recruiting
Cleveland Clinic
Cleveland, Ohio, United States
Recruiting
Oregon Health & Science University
Portland, Oregon, United States
Johannes Steiner, MD
Recruiting
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States
Keshava Rajagopal, MD
Recruiting
Medical University of South Carolina
Charleston, South Carolina, United States
Arman Kilic
Recruiting
Baptist - Memphis (stern)
Memphis, Tennessee, United States
Recruiting
Baylor University Medical Center, Part of Baylor Scott & White Health
Dallas, Texas, United States
Recruiting
Ut Southwestern Medical Center
Dallas, Texas, United States
Matthias Peltz
Recruiting

7 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 28 Oct 2024
Primary completion: 29 Feb 2028
Completion: 31 Dec 2028
Last update posted: 17 Aug 2026
Registered enrollment: 780
Registry id: NCT06310031

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.