Clinical trialNCT06326411RecruitingPhase 1Interventional

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

SponsorNested Therapeutics, IncEnrollment230GliomaMAPK Pathway Gene MutationMEK MutationMelanomaNSCLCOncology+3 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

23 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

the Kinghorn Cancer Center, St. Vincent'S Health Network
Darlinghurst, New South Wales, Australia
Jia (Jenny) Liu, MD
Recruiting
Scientia Clinical Research, Ltd
Randwick, New South Wales, Australia
Completed
Gallipoli Medical Research Centre- Greenslopes Private Hospital
Greenslopes, Queensland, Australia
Victoria Atkinson, MD
Recruiting
Southern Oncology Research Unit
Adelaide, South Australia, Australia
Ganessan Kichenadasse, MD
Recruiting
Cabrini Health Limited
Malvern, Victoria, Australia
Prachi Bhave, MD
Recruiting
Cabrini Hospital
Malvern, Victoria, Australia
Prachi Bhave, MD
Recruiting

United States

Ucsf Helen Diller Family Comprehensive Cancer Center
San Francisco, California, United States
Virun Monga, MD
Recruiting
Ucla Hematology/oncology
Westwood, Los Angeles, California, United States
Bartosz Chmielowski, MD
Recruiting
Sarah Cannon Research Institute at Health One
Denver, Colorado, United States
Gerald Falchook, MD, MS
Recruiting
Yale Cancer Center
New Haven, Connecticut, United States
Completed
Moffitt Cancer Center
Tampa, Florida, United States
Ahmad Tarhini, MD
Recruiting
Roswell Park
Buffalo, New York, United States
Igor Puzanov, MD
Recruiting
Columbia University Medical Center
New York, New York, United States
Benjamin Herzberg, MD
Recruiting
Laura & Isaac Perlmutter Cancer Center at Nyu Langone Health
New York, New York, United States
Janice Mehnert, MD
Recruiting
Memorial Slone Kettering Cancer Center
New York, New York, United States
Monica Chen, MD
Recruiting
Upmc Hillman Cancer Center
Pittsburgh, Pennsylvania, United States
Jason Luke, MD
Recruiting
Scri Oncology Partners
Nashville, Tennessee, United States
Meredith McKean, MD, MPH
Recruiting
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, United States
Jordan D Berlin, MD
Recruiting
Next Oncology - Austin
Austin, Texas, United States
Active, not recruiting
Next Oncology - Dallas
Dallas, Texas, United States
Active, not recruiting
Md Anderson Cancer Center
Houston, Texas, United States
Sarina Piha-Paul, MD
Recruiting
Start Moutain Region
West Valley City, Utah, United States
Completed
Next Oncology - Virginia
Fairfax, Virginia, United States
Mohamad Salkeni, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 9 Apr 2024
Primary completion: 30 Nov 2028
Completion: 30 Nov 2029
Last update posted: 20 Apr 2026
Registered enrollment: 230
Registry id: NCT06326411

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.