Impact of Discontinuing Hypertonic Saline in People With CF on Highly Effective CFTR Modulators- A SIMPLIFY Sub-Study
Summary
The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →
Investigators
The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.
- Alex Gifford, MD, FCCP
Dartmouth-Hitchcock Medical Center
Principal Investigator - Nicole Mayer-Hamblett, PhD
University of Washington/Seattle Children's
Principal Investigator
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
81 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- University of Alabama at Birmingham
Birmingham, Alabama, United States
- Providence Alaska Medical Center
Anchorage, Alaska, United States
- Tucson Cystic Fibrosis Center
Tucson, Arizona, United States
- Arkansas Children'S Hospital
Little Rock, Arkansas, United States
- Miller Children'S and Women'S Hospital Long Beach
Long Beach, California, United States
- Choc Children'S Hospital
Orange, California, United States
- Stanford University Medical Center
Palo Alto, California, United States
- Rady Children'S Hospital and Health Center at the University of California San Diego
San Diego, California, United States
- University of California, San Francisco - Adult Center
San Francisco, California, United States
- University of California, San Francisco - Peds Center
San Francisco, California, United States
- Children'S Hospital Colorado
Aurora, Colorado, United States
- National Jewish Health
Denver, Colorado, United States
- Yale University School of Medicine
New Haven, Connecticut, United States
- University of Florida
Gainesville, Florida, United States
- Nemours Children'S Clinic - Jacksonville
Jacksonville, Florida, United States
- Central Florida Pulmonary Group
Orlando, Florida, United States
- the Nemours Children'S Clinic - Orlando
Orlando, Florida, United States
- Nemours Children'S Clinic - Pensacola
Pensacola, Florida, United States
- All Children'S Hospital
St. Petersburg, Florida, United States
- Tampa General Hospital
Tampa, Florida, United States
- Emory University
Atlanta, Georgia, United States
- Saint Luke'S Cystic Fibrosis Center of Idaho
Boise, Idaho, United States
- Northwestern University
Chicago, Illinois, United States
- Osf Saint Francis Medical Center
Peoria, Illinois, United States
- Riley Hospital for Children
Indianapolis, Indiana, United States
- University of Iowa
Iowa City, Iowa, United States
- University of Kansas Medical Center
Kansas City, Kansas, United States
- University of Kentucky
Lexington, Kentucky, United States
- University of Louisville
Louisville, Kentucky, United States
- Tulane University
Metairie, Louisiana, United States
- Maine Medical Partners Pediatric Specialty Care
Portland, Maine, United States
- Johns Hopkins University
Baltimore, Maryland, United States
- Boston Children'S Hospital
Boston, Massachusetts, United States
- University of Michigan, Michigan Medicine
Ann Arbor, Michigan, United States
- Wayne State University Harper University Hospital
Detroit, Michigan, United States
- Corewell Health Helen Devos
Grand Rapids, Michigan, United States
- Children'S Hospitals and Clinics of Minnesota
Minneapolis, Minnesota, United States
- the Minnesota Cystic Fibrosis Center
Minneapolis, Minnesota, United States
- Children'S Mercy Kansas City
Kansas City, Missouri, United States
- Washington University School of Medicine
St Louis, Missouri, United States
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 25 Aug 2020
- Primary completion
- 11 Jul 2022
- Completion
- 11 Jul 2022
- Last update posted
- 1 Oct 2024
- Registered enrollment
- 370
- Registry id
- NCT06350461
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.