Clinical trialNCT06365060RecruitingObservational

Screening for AL Amyloidosis in Smoldering Multiple Myeloma

SponsorTufts Medical CenterEnrollment400Smoldering Multiple Myeloma

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

In this multicenter study, we will recruit 400 patients 40 years of age or older at 15 centers with a diagnosis of smoldering multiple myeloma (SMM), a group of patients for whom standard of care is observation not treatment. The main goal of this study is to screen for the diagnosis of light-chain amyloidosis (AL) before the onset of symptomatic disease and to develop a training set for a likelihood algorithm.

clinicaltrials.gov ↗

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

13 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama Hospital
Birmingham, Alabama, United States
Susan Bal, MD
Recruiting
Cedars-Sinai Medical Center
Los Angeles, California, United States
Robert Vescio, MD
Recruiting
University of California, San Francisco
San Francisco, California, United States
Tom Martin, MD
Recruiting
Cleveland Clinic Florida, Weston Hospital
Weston, Florida, United States
Chakra Chaulagain, MD
Recruiting
Tufts Medical Center
Boston, Massachusetts, United States
Raymond Comenzo, MD
Recruiting
Columbia University Irving Medical Center
New York, New York, United States
Suzanne Lentzsch, MD
Recruiting
Memorial Sloan Kettering Cancer Center
New York, New York, United States
Heather Landau, MD
Recruiting
Atrium Health Levine Cancer Institute
Charlotte, North Carolina, United States
Cindy Varga, MD
Recruiting
Unc Lineberger Comprehensive Cancer Center
Durham, North Carolina, United States
Sascha Tuchman, MD
Recruiting
the Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States
Naresh Bumma, MD
Recruiting
Ut Southwestern, Harold C. Simmons Comprehensive Cancer Center
Dallas, Texas, United States
Larry Anderson, MD
Not, yet, recruiting
University of Utah, Huntsman Cancer Hospital
Salt Lake City, Utah, United States
Amandeep Godara, MD
Recruiting
Vcu Medical Center
Richmond, Virginia, United States
Hashim Mann, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 May 2024
Primary completion: 27 Feb 2029
Completion: 27 Feb 2029
Last update posted: 6 Aug 2025
Registered enrollment: 400
Registry id: NCT06365060

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.