Clinical trialNCT06374238RecruitingInterventional

Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain

SponsorUniversity of PittsburghEnrollment470PainSickle Cell Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain, opioid use, and healthcare utilization among AYAs with SCD. It also seeks to understand the role of personalized peer support in enhancing engagement and outcomes of digital CBT interventions. By leveraging existing infrastructure for delivering virtual peer support interventions, tailored digital CBT programs for individuals with SCD, and partnerships with CBOs, the study aims to provide valuable insights into the feasibility and effectiveness of digital CBT as a pain management strategy for this vulnerable population.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Alicia Colvin, PhD
University of Pittsburgh
Principal Investigator
clinicaltrials.gov ↗
Ana Radovic, MD
University of Pittsburgh
Principal Investigator
clinicaltrials.gov ↗
Charles Jonassaint, PhD
University of Pittsburgh
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

14 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of South Alabama Medical Center
Mobile, Alabama, United States
Antwan Hogue, MDArdie Pack-Mabien, PhD
Recruiting
Ucla Mattel Children'S Hospital Ronald Reagan Hospital
Los Angeles, California, United States
Satiro De Oliveira, MD
Recruiting
Connecticut Children'S Medical Center
Hartford, Connecticut, United States
William Zempsky, MD
Recruiting
Children'S Healthcare of Atlanta
Atlanta, Georgia, United States
Carlton Dampier, MD
Recruiting
Ann and Robert H. Lurie Children'S Hospital of Chicago
Chicago, Illinois, United States
Robert Liem, MD
Recruiting
the Regents of the University of Michigan
Ann Arbor, Michigan, United States
Eric Scott, PhD
Recruiting
Rutgers New Jersey Medical School
Newark, New Jersey, United States
Ashwin Sridharan, MD
Recruiting
Weil Cornell Medical College
New York, New York, United States
Maria DeSancho, MD
Recruiting
University of Rochester Medical Center
Rochester, New York, United States
Suzie Noronha, MD
Recruiting
Wake Forest Baptist Hospital
Durham, North Carolina, United States
Alex George, MD
Recruiting
East Carolina University Health Medical Center
Greenville, North Carolina, United States
Darla Liles, MD
Recruiting
Upmc Children'S Hospital of Pittsburgh
Pittsburgh, Pennsylvania, United States
Dr. Cheryl Hillery, MD
Recruiting
Upmc University of Pittsburgh Classical Hematology Adult Clinic
Pittsburgh, Pennsylvania, United States
Ana Radovic, MDLaura De Castro, MD
Recruiting
Virginia Commonwealth University
Richmond, Virginia, United States
Wally Smith, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 10 Mar 2025
Primary completion: 31 Jul 2027
Completion: 31 May 2028
Last update posted: 7 Jan 2026
Registered enrollment: 470
Registry id: NCT06374238

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.