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Clinical trialNCT06401356RecruitingPhase 3Interventional

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

SponsorNovartis PharmaceuticalsEnrollment50Advanced MalignanciesHematologic MalignancySolid Tumor
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate the long-term safety and the clinical benefit of pelabresib in patients with hematological and/or solid tumor indications or advanced malignancies. Additionally, participants previously enrolled in studies with pelabresib who received placebo or participants who discontinued pelabresib (for any other reason than participating in this extension study), may be enrolled in this extension study to evaluate the survival and leukemia-free survival (for patients with hematological malignancies) or only the Survival Follow-up (for all the other patients).

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

15 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Belgium
  • Novartis Investigative Site

    Antwerp, Belgium

    Recruiting
  • Novartis Investigative Site

    Bruges, Belgium

    Recruiting
Italy
  • Novartis Investigative Site

    Florence, FI, Italy

    Recruiting
  • Novartis Investigative Site

    Varese, VA, Italy

    Recruiting
  • Novartis Investigative Site

    Novara, Italy

    Recruiting
Netherlands
  • Novartis Investigative Site

    Amsterdam, Netherlands

    Recruiting
United Kingdom
  • Novartis Investigative Site

    Cardiff, United Kingdom

    Recruiting
  • Novartis Investigative Site

    Glasgow, United Kingdom

    Recruiting
  • Novartis Investigative Site

    London, United Kingdom

    Recruiting
United States
  • University of California la

    Los Angeles, California, United States

    Gary Schiller
    Recruiting
  • Mayo Clinic Jacksonville

    Jacksonville, Florida, United States

    Candido Rivera
    Recruiting
  • Northwestern University

    Chicago, Illinois, United States

    Brady L Stein
    Recruiting
  • Uni of Michigan Health System

    Ann Arbor, Michigan, United States

    Moshe Talpaz
    Recruiting
  • Mt Sinai Medical Center

    New York, New York, United States

    Marina Kremyanskaya
    Recruiting
  • New York Presbyterian Hospital

    New York, New York, United States

    Joseph Scandura
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Pelabresib
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
13 Aug 2024
Primary completion
2 Jun 2027
Completion
30 Jun 2027
Last update posted
11 Jun 2026
Registered enrollment
50
Registry id
NCT06401356

Cross-registrations

EU-CTR / CTIS (EudraCT)2023-508950-24-00

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.