Clinical trialNCT06422806RecruitingPhase 3Interventional

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

SponsorNational Cancer Institute (NCI)Enrollment365Metastatic Dedifferentiated LiposarcomaMetastatic Undifferentiated Pleomorphic SarcomaStage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8Unresectable Dedifferentiated LiposarcomaUnresectable Undifferentiated Pleomorphic Sarcoma

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Seth M Pollack
ECOG-ACRIN Cancer Research Group
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

256 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Arthur J E Child Comprehensive Cancer Centre
Calgary, Alberta, Canada
Xiaolan Feng
Recruiting
Cross Cancer Institute
Edmonton, Alberta, Canada
Quincy S. Chu
Recruiting
Bcca-Vancouver Cancer Centre
Vancouver, British Columbia, Canada
Jamie Feng
Recruiting
Cancercare Manitoba
Winnipeg, Manitoba, Canada
Shantanu Banerji
Recruiting
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, Canada
Courtney Coschi
Recruiting
Ottawa Hospital and Cancer Center-General Campus
Ottawa, Ontario, Canada
Garth A. Nicholas
Recruiting
University Health Network-Princess Margaret Hospital
Toronto, Ontario, Canada
Abdulazeez Salawu
Recruiting
Chu de Quebec-L'Hotel-Dieu de Quebec (hdq)
Québec, Quebec, Canada
Christopher Lemieux
Recruiting

Puerto Rico

Pan American Center for Oncology Trials Llc - Dorado
Dorado, Puerto Rico
Marcia R. Cruz-Correa
Recruiting
Pan American Center for Oncology Trials Llc
San Juan, Puerto Rico
Marcia R. Cruz-Correa
Recruiting
Pan American Center for Oncology Trials Llc - Ciudadela
San Juan, Puerto Rico
Marcia R. Cruz-Correa
Recruiting

United States

Mayo Clinic Hospital in Arizona
Phoenix, Arizona, United States
Mahesh Seetharam
Recruiting
Banner University Medical Center - Tucson
Tucson, Arizona, United States
Anna Roshal
Recruiting
University of Arizona Cancer Center-North Campus
Tucson, Arizona, United States
Anna Roshal
Recruiting
Kaiser Permanente Dublin
Dublin, California, United States
Tatjana Kolevska
Recruiting
Kaiser Permanente-Fremont
Fremont, California, United States
Tatjana Kolevska
Recruiting
Kaiser Permanente Fresno Orchard Plaza
Fresno, California, United States
Tatjana Kolevska
Recruiting
Kaiser Permanente-Fresno
Fresno, California, United States
Tatjana Kolevska
Recruiting
Uc San Diego Moores Cancer Center
La Jolla, California, United States
Hirotaka Miyashita
Recruiting
Cedars-Sinai Medical Center
Los Angeles, California, United States
James S. Hu
Recruiting
Keck Medicine of Usc Koreatown
Los Angeles, California, United States
Mark Agulnik
Recruiting
Los Angeles General Medical Center
Los Angeles, California, United States
Mark Agulnik
Recruiting
Usc / Norris Comprehensive Cancer Center
Los Angeles, California, United States
Mark Agulnik
Recruiting
Kaiser Permanente- Modesto Mob Ii
Modesto, California, United States
Tatjana Kolevska
Recruiting
Kaiser Permanente-Modesto
Modesto, California, United States
Tatjana Kolevska
Recruiting
Usc Norris Oncology/hematology-Newport Beach
Newport Beach, California, United States
Mark Agulnik
Recruiting
Kaiser Permanente-Oakland
Oakland, California, United States
Tatjana Kolevska
Recruiting
Stanford Cancer Institute Palo Alto
Palo Alto, California, United States
Nam Bui
Recruiting
Va Palo Alto Health Care System
Palo Alto, California, United States
Suspended
Huntington Memorial Hospital
Pasadena, California, United States
James S. Hu
Recruiting
Kaiser Permanente-Roseville
Roseville, California, United States
Tatjana Kolevska
Recruiting
Kaiser Permanente Downtown Commons
Sacramento, California, United States
Tatjana Kolevska
Recruiting
Kaiser Permanente-South Sacramento
Sacramento, California, United States
Tatjana Kolevska
Recruiting
Kaiser Permanente-San Francisco
San Francisco, California, United States
Tatjana Kolevska
Recruiting
Ucsf Medical Center-Mission Bay
San Francisco, California, United States
Varun Monga
Recruiting
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, United States
Tatjana Kolevska
Recruiting
Kaiser Permanente San Leandro
San Leandro, California, United States
Tatjana Kolevska
Recruiting
Kaiser San Rafael-Gallinas
San Rafael, California, United States
Tatjana Kolevska
Recruiting
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, United States
Tatjana Kolevska
Recruiting
Kaiser Permanente-Santa Rosa
Santa Rosa, California, United States
Tatjana Kolevska
Recruiting

216 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 11 Sept 2024
Primary completion: 30 Jun 2035
Completion: 30 Jun 2035
Last update posted: 1 Jul 2026
Registered enrollment: 365
Registry id: NCT06422806

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.