FindMyKOL
Clinical trialNCT06445738RecruitingInterventional

Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion (PROSPECTIVE)

SponsorBreast Cancer Trials, Australia and New ZealandEnrollment1,400Breast CancerBreast Cancer Female
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The PROSPECTIVE trial aims to find out if using the results of Magnetic Resonance Imaging (MRI) for early breast cancer can select people to not have radiotherapy and still have a low chance of the cancer coming back after surgery. The main question it aims to answer is: \* Will cancer come back in the same breast as the original cancer in patients who have surgery for their breast cancer, but who don't have radiotherapy afterwards because the results of an MRI before surgery showed favourable characteristics for not having radiotherapy.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • the Chris O'Brien Lifehouse

    Camperdown, New South Wales, Australia

    Sanjay Warrier, A/Prof
    Not, yet, recruiting
  • Lake Macquarie Private Hospital

    Gateshead, New South Wales, Australia

    Shanta Velaiutham, Dr
    Not, yet, recruiting
  • Mater Hospital, Sydney

    North Sydney, New South Wales, Australia

    Andrew Spillane, Prof
    Recruiting
  • Westmead Hospital

    Westmead, New South Wales, Australia

    Elisabeth Elder, Dr
    Not, yet, recruiting
  • Royal Adelaide Hospital

    Adelaide, South Australia, Australia

    Janne Bingham, Dr
    Not, yet, recruiting
  • Monash Cancer Centre (mmc Moorabbin)

    Clayton, Victoria, Australia

    Corinne Wei Leng Ooi, Dr
    Recruiting
  • the Royal Melbourne Hospital

    Melbourne, Victoria, Australia

    Bruce Mann, Prof
    Recruiting
United States
  • Ucsf Breast Care Center

    San Francisco, California, United States

    Michael Alvarado, Prof
    Not, yet, recruiting
  • Baylor St Luke'S Medical Centre

    Houston, Texas, United States

    Alastair Thompson, Prof
    Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
6 Jun 2025
Primary completion
30 Jun 2032
Completion
30 Jun 2039
Last update posted
15 Jan 2026
Registered enrollment
1,400
Registry id
NCT06445738
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.