Clinical trialNCT06451757RecruitingPhase 3Interventional

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

SponsorKhondrion BVEnrollment220Maternally Inherited Diabetes and Deafness (MIDD)Mitochondrial DNA tRNALeu(UUR) m.3243A<G MutationMitochondrial DiseasesMitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Denmark

Rigshospitalet, University of Copenhagen
Kopenhagen, Region Sjælland, Denmark
Nicolai Rasmus Preisler, Dr.
Not, yet, recruiting

France

Chu de Bordeaux - Hôpital Pellegrin Service Gynecologie Obstetrique
Bordeaux, Gironde, France
Aurelien Trimouille, Dr.
Not, yet, recruiting
Groupe Hospitalier Pitie-Salpetriere - Charles-Foix Clinical Investigation Center Paris-Est
Paris, Paris, France
Fanny Mochel, Dr.
Not, yet, recruiting

Germany

Klinikum Der Universität München Friedrich-Baur-Institut
München, Germany
Boriana Buechner, Dr.Thomas Klopstock, Prof. Dr.
Recruiting

Italy

Fondazione Irccs Istituto Neurologico Carlo Besta
Milan, Italy
Costanza Lamperti, Dr.
Recruiting

Netherlands

Radboud University Medical Center
Nijmegen, Gelderland, Netherlands
Mirian Janssen, MD, PhD
Recruiting

United Kingdom

University College London Hospitals Nhs Foundation Trust National Hospital for Neurology and Neurosurgery
London, Greater London, United Kingdom
Robbert Pitceathly, Dr.
Recruiting

United States

Massachusetts General Hospital
Boston, Massachusetts, United States
Amel Karaa, Dr.
Not, yet, recruiting
Cleveland Clinic Neurological Institute Mellen Center
Cleveland, Ohio, United States
Sumit Parikh, Dr.
Not, yet, recruiting
the University of Texas Health Science Center at Houston
Houston, Texas, United States
Mary Koenig, Dr.Sam Nicholas Russo, Dr.
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 14 Apr 2026
Primary completion: 30 Sept 2028
Completion: 30 Sept 2028
Last update posted: 29 Jun 2026
Registered enrollment: 220
Registry id: NCT06451757

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.