Clinical trialNCT06462547TerminatedPhase 2Interventional

ADAPT Study: Long-term Safety Study of INZ-701 in Patients With ENPP1 Deficiency and ABCC6 Deficiency

SponsorInozyme PharmaEnrollment22Arterial CalcificationAutosomal Recessive Hypophosphatemic Rickets Type 2Ectonucleotide Pyrophosphatase/phosphodiesterase1 DeficiencyGene MutationsPseudoxanthoma Elasticum

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study (Study INZ701-304 \[ADAPT\]) is to assess the long-term safety of INZ-701 in patients with ENPP1 Deficiency or ABCC6 Deficiency who have received INZ-701 in an existing clinical study and choose to continue dosing for the potential treatment of their condition.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Kurt Gunter, MD
Inozyme Pharma, Inc.
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

France

Necker-Enfants Malades Hospital
Paris, France

Germany

Universitätsklinikum Hamburg-Eppendorf (uke)
Hamburg, Germany

United Kingdom

Medical Research Network Ltd.
Milton Keynes, United Kingdom

United States

Mayo Clinic
Rochester, Minnesota, United States
Clinilabs Drug Development Corporation
Eatontown, New Jersey, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

INZ-701

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 19 Jun 2024
Primary completion: 30 Sept 2026
Completion: 30 Sept 2026
Last update posted: 19 Oct 2026
Registered enrollment: 22
Registry id: NCT06462547

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.