Clinical trialNCT06465199RecruitingPhase 1/PHASE2Interventional

Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

SponsorMilton S. Hershey Medical CenterEnrollment289Atypical Teratoid/Rhabdoid TumorDIPG Brain TumorDiffuse Intrinsic Pontine GliomaEmbryonal Tumor With Multilayered RosettesEwing SarcomaNeuroblastoma+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Giselle Saulnier Sholler, MD
Penn State Health Children's Hospital
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

12 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama/children'S of Alabama
Birmingham, Alabama, United States
Elizabeth Alva
Recruiting
Arkansas Children'S Hospital
Little Rock, Arkansas, United States
Kevin Bielamowicz
Recruiting
Connecticut Children'S Hospital
Hartford, Connecticut, United States
Michael Isakoff
Recruiting
Nicklaus Children'S Hospital
Miami, Florida, United States
Guillermo De Angulo
Recruiting
Arnold Palmer Hospital for Children
Orlando, Florida, United States
Jamie Libes-Bander
Recruiting
St. Joseph'S Children'S Hospital
Tampa, Florida, United States
Don Eslin
Recruiting
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, United States
Kelley Hutchins
Recruiting
Children'S Mercy Hospitals and Clinics
Kansas City, Kansas, United States
Kevin Ginn
Recruiting
Cardinal Glennon Children'S Medical Center
St Louis, Missouri, United States
William Ferguson
Recruiting
Penn State Milton S. Hershey Medical Center and Children'S Hospital
Hershey, Pennsylvania, United States
Valerie Brown
Recruiting
Monroe Carrell Jr. Children'S Hospital at Vanderbilt
Nashville, Tennessee, United States
Daniel Benedetti
Recruiting
Children'S Medical Center
Dallas, Texas, United States
Tanya Watt
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 13 May 2026
Primary completion: 31 May 2033
Completion: 31 May 2035
Last update posted: 1 Jul 2026
Registered enrollment: 289
Registry id: NCT06465199

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.