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Clinical trialNCT06496750Active, not recruitingPhase 2Interventional

Ketamine for Methamphetamine Use Disorder

SponsorUniversity of Texas Southwestern Medical CenterEnrollment120Methamphetamine AbuseSubstance UseSubstance Use Disorders
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study aims to determine whether treatment response with IV ketamine is superior to treatment response with IV midazolam in adults with moderate to severe MUD. The study design is a 12-week randomized, double-blind, controlled trial comparing intravenous (IV) ketamine against IV midazolam, delivered over six weeks in 120 adults with moderate to severe methamphetamine use disorder (MUD).
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Alameda Health System

    San Leandro, California, United States

  • Interdisciplinary Substance Use and Brain Injury Facility

    Albuquerque, New Mexico, United States

  • Addiction Institute of Mount Sinai

    New York, New York, United States

  • Prisma Health

    Greenville, South Carolina, United States

  • Ut Southwestern Medical Center

    Dallas, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

KetamineMidazolam →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
11 Sept 2024
Primary completion
31 Aug 2026
Completion
31 Oct 2026
Last update posted
11 Aug 2026
Registered enrollment
120
Registry id
NCT06496750
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.