Clinical trialNCT06541262RecruitingPhase 1/PHASE2Interventional

Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

SponsorMilton S. Hershey Medical CenterEnrollment104Ewing SarcomaLiposarcomaNeuroblastomaOsteosarcomaRhabdomyosarcoma

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Chandrika Behura, MD
Penn State Health Children's Hospital
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

22 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Uhc Sainte-Justine
Montreal, Quebec, Canada
Monia Marzouki
Recruiting

United States

University of Alabama/children'S of Alabama
Birmingham, Alabama, United States
Elizabeth Alva
Recruiting
Phoenix Children'S Hospital
Phoenix, Arizona, United States
Francis Eshun
Recruiting
Ucsf Benioff Children'S Hospital Oakland
Oakland, California, United States
Jennifer Michlitsch
Recruiting
Rady Children'S Hospital
San Diego, California, United States
William Roberts
Recruiting
Connecticut Children'S Hospital
Hartford, Connecticut, United States
Michael Isakoff
Recruiting
University of Florida
Gainesville, Florida, United States
Joanne Lagmay
Recruiting
Nicklaus Children'S Hospital
Miami, Florida, United States
Maggie Fader
Recruiting
Arnold Palmer Hospital for Children
Orlando, Florida, United States
Jaime Libes-Bander
Recruiting
All Children'S Hospital Johns Hopkins Medicine
St. Petersburg, Florida, United States
Jennifer Dean
Recruiting
St. Joseph'S Children'S Hospital
Tampa, Florida, United States
Don Eslin
Recruiting
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, United States
Kelley Hutchins
Recruiting
Norton Children'S Research Institute/affiliated With University of Louisville School of Medicine
Louisville, Kentucky, United States
Michael Ferguson
Recruiting
Children'S Mercy Hospitals and Clinics
Kansas City, Missouri, United States
Kevin Ginn
Recruiting
Cardinal Glennon Children'S Medical Center
St Louis, Missouri, United States
William Ferguson
Recruiting
Hackensack University Medical Center
Hackensack, New Jersey, United States
Katharine Offer
Recruiting
Penn State Milton S. Hershey Medical Center and Children'S Hospital
Hershey, Pennsylvania, United States
Valerie Brown
Recruiting
Hasbro Children'S Hospital
Providence, Rhode Island, United States
Bradley DeNardo
Recruiting
Monroe Carrell Jr. Children'S Hospital at Vanderbilt
Nashville, Tennessee, United States
Daniel Benedetti
Recruiting
Children'S Medical Center
Dallas, Texas, United States
Tanya Watt
Recruiting
Primary Children'S Hospital
Salt Lake City, Utah, United States
Matthew Dietz
Recruiting
Virginia Commonwealth University
Richmond, Virginia, United States
Madhu Gowda
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Oct 2024
Primary completion: 1 Nov 2030
Completion: 1 Nov 2035
Last update posted: 2 Jul 2026
Registered enrollment: 104
Registry id: NCT06541262

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.