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Clinical trialNCT06569823Active, not recruitingPhase 1/PHASE2Interventional

Safety and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adults 50 Years of Age and Over

SponsorDynavax Technologies CorporationEnrollment764Herpes ZosterShinglesVaccine-Preventable Diseases
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a randomized, active-controlled, observer-blinded, dose-escalation multi-center trial of 2 doses of an investigational HZ vaccine (Z-1018) in approximately 764 healthy adults.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

16 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Paratus Clinical Research Western Syndney

    Blacktown, New South Wales, Australia

  • Emeritus Research

    Botany, New South Wales, Australia

  • Canopy Clinical Northern Beaches

    Brookvale, New South Wales, Australia

  • Paratus Clinical Research Central Coast

    Kanwal, New South Wales, Australia

  • Sutherland Shire Clinical Research

    Miranda, New South Wales, Australia

  • Innovate Clinical Research

    Waitara, New South Wales, Australia

  • Canopy Clinical Wollongong

    Wollongong, New South Wales, Australia

  • Paratus Clinical Research Brisbane

    Herston, Queensland, Australia

  • Veritus Research

    Bayswater, Victoria, Australia

  • Emeritus Research

    Camberwell, Victoria, Australia

  • Doherty Clinical Trials Limited

    East Melbourne, Victoria, Australia

New Zealand
  • Optimal Clinical Trials Ltd - Central

    Auckland, New Zealand

  • Optimal Clinical Trials Ltd - North

    Auckland, New Zealand

  • New Zealand Clinical Research

    Christchurch, New Zealand

  • Momentum Clinical Research Kapiti

    Wellington, New Zealand

  • Momentum Wellington

    Wellington, New Zealand

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Varicella zoster virus glycoprotein E →Z-1018
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
17 Jun 2024
Primary completion
30 Nov 2027
Completion
30 Nov 2031
Last update posted
29 May 2026
Registered enrollment
764
Registry id
NCT06569823
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.