Clinical trialNCT06608823RecruitingInterventional

ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

SponsorJenaValve Technology, Inc.Enrollment1,016Aortic InsufficiencyAortic RegurgitationAortic Valve Insufficiency

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To demonstrate non-inferiority of the Trilogy Transcatheter Heart Valve (THV) System compared with surgical aortic valve replacement (SAVR) for treatment of subjects with clinically significant native aortic regurgitation (AR)

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Hendrik Treede, MD
Department of Cardiovascular Surgery Johannes-Gutenberg University
Principal Investigator
clinicaltrials.gov ↗
Raj Makkar, MD
Cedars-Sinai Medical Center
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Torsten P Vahl, MD
Columbia University
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Vinod H Thourani, MD
Piedmont Heart Institute
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

29 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Cpmc Sutter Health
Burlingame, California, United States
David Daniels, MD
Recruiting
Scripps Health
La Jolla, California, United States
Curtiss Stinis, MD
Recruiting
Cedars-Sinai Medical Center
Los Angeles, California, United States
Raj Makkar, MD →
Recruiting
Los Robles Medical Center
Thousand Oaks, California, United States
Saibal Kar, MD
Recruiting
Medstar Washington Hospital Center
Washington D.C., District of Columbia, United States
Ron Waksman, MD
Recruiting
Baycare Health
Clearwater, Florida, United States
Joshua Rovin, MD
Recruiting
Hca North Florida
Gainesville, Florida, United States
Charles Klodell, MD
Recruiting
Emory University Hospital
Atlanta, Georgia, United States
Adam Greenbaum, MD
Recruiting
Piedmont Healthcare
Atlanta, Georgia, United States
Pradeep Yadav, MD
Recruiting
Heart Care Centers of Il / Hinsdale Hospital
Chicago, Illinois, United States
Ravi Ramana, DO
Recruiting
Ascension St. Vincent Heart Center
Carmel, Indiana, United States
Ezequiel Munoz, MD
Recruiting
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States
Marie-France Poulin, MD
Recruiting
University of Michigan
Ann Arbor, Michigan, United States
Stanley Chetcuti, MD
Recruiting
Henry Ford Health
Detroit, Michigan, United States
Tiberio Frisoli
Recruiting
Minneapolis Heart Institute Foundation
Minneapolis, Minnesota, United States
Mario Goessl, MD
Recruiting
Washington University - Barnes Jewish Hospital
St Louis, Missouri, United States
Alan Zajarias, MD
Recruiting
Robert Wood Johnson University Hospital
New Brunswick, New Jersey, United States
Mark Russo, MD
Recruiting
Buffalo General Medical Center
Buffalo, New York, United States
Vijay Iyer, MD
Recruiting
Columbia University Medical Center
New York, New York, United States
Torsten Vahl, MD
Recruiting
the Christ Hospital
Cincinnati, Ohio, United States
Santiago Garcia, MD
Recruiting
the Cleveland Clinic Foundation
Cleveland, Ohio, United States
Amar Krishnaswamy, MD
Recruiting
Ohio Health
Columbus, Ohio, United States
Carlos Sanchez, MD
Recruiting
Oregon Health & Science University (ohsu)
Portland, Oregon, United States
Harsh Golwala, MD
Recruiting
Lankenau Institute for Medical Research
Philadelphia, Pennsylvania, United States
Basel Ramlawi, MD
Recruiting
Houston Methodist Research Institute
Houston, Texas, United States
Marvin Atkins, MD
Recruiting
Baylor Scott & White Health
Plano, Texas, United States
Srini Potluri, MD
Recruiting
Intermountain Health
Murray, Utah, United States
Brian Whisenant, MD
Recruiting
Sentara Norfolk
Norfolk, Virginia, United States
Matthew Summers, MD
Recruiting
University of Washington
Seattle, Washington, United States
Christine Chung, MDScott DeRoo, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 18 Jun 2025
Primary completion: 30 Jun 2027
Completion: 29 Feb 2036
Last update posted: 7 Jul 2026
Registered enrollment: 1,016
Registry id: NCT06608823

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.