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Clinical trialNCT06648434RecruitingPhase 1Interventional

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

SponsorWashington University School of MedicineEnrollment51Cancer of the PancreasMetastatic Pancreatic Ductal AdenocarcinomaPancreatic Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The investigators hypothesize that MK2 inhibition may improve efficacy of mFOLFIRINOX chemotherapy for patients with pancreatic ductal adenocarcinoma (PDAC).

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Washington University School of Medicine

    St Louis, Missouri, United States

    Benjamin Tan, M.D.Chunjie Li, M.D., Ph.D.Esther Lu, Ph.D.Kian-Huat Lim, M.D., Ph.D.Mark O'Hara, M.D.Max Wattenberg, M.D.Moh'd Khushman, M.D.Nikolaos Andreatos, M.D.Nikolaos Trikalinos, M.D.Olivia Aranha, M.D., Ph.D.Patrick Grierson, M.D., Ph.D.Rama Suresh, M.D.Ramon Jin, M.D., Ph.D.
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

ZunsemetinibMFOLFIRINOX
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
13 Jun 2025
Primary completion
30 Jun 2027
Completion
31 May 2030
Last update posted
30 Apr 2026
Registered enrollment
51
Registry id
NCT06648434

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.