Clinical trialNCT06651580RecruitingObservational

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

SponsorM.D. Anderson Cancer CenterEnrollment1,600Chronic PancreatitisExocrine Pancreas CarcinomaRecurrent Acute Pancreatitis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This clinical trial collects blood, saliva, urine, or stool samples to help identify possible genetic mutations that may increase a person's chance at developing pancreatic cancer. Finding genetic markers among pediatric patients with acute recurrent pancreatitis and chronic pancreatitis may help identify patients who are at risk of pancreatic cancer.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Ying Yuan, PHD
M.D. Anderson Cancer Center
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

26 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Sydney Children'S Hospital
Randwick, New South Wales, Australia
Keith Ooi
Recruiting

Canada

Hospital for Sick Children
Toronto, Ontario, Canada
Tanja Gonska
Recruiting
the Montreal Children'S Hospital of the Muhc
Montreal, Quebec, Canada
Veronique Morinville
Recruiting

Israel

Hadassah University Hospital
Jerusalem, Israel
Michael Wilschanski
Recruiting

United States

Cedars Sinai Medical Center
Los Angeles, California, United States
Quin Liu
Recruiting
Children'S Hospital Los Angeles
Los Angeles, California, United States
Yuhua Zheng
Recruiting
Ucsf Benioff Children'S Hospital Oakland
Oakland, California, United States
Emily Perito
Recruiting
Stanford Cancer Institute Palo Alto
Palo Alto, California, United States
Zachary Sellers
Recruiting
University of Colorado
Denver, Colorado, United States
Jacob Mark
Recruiting
Emory University Hospital/winship Cancer Institute
Atlanta, Georgia, United States
Reuven "Zev" Cohen
Recruiting
Riley Hospital for Children
Indianapolis, Indiana, United States
Brian McFerron
Recruiting
University of Iowa/holden Comprehensive Cancer Center
Iowa City, Iowa, United States
Aliye Uc
Recruiting
Ochsner Medical Center Jefferson
New Orleans, Louisiana, United States
Matthew Giefer
Recruiting
Johns Hopkins University/sidney Kimmel Cancer Center
Baltimore, Maryland, United States
Kenneth Ng
Recruiting
Boston Children'S Hospital
Boston, Massachusetts, United States
Amit Grover
Recruiting
University of Minnesota/masonic Children'S Hospital
Minneapolis, Minnesota, United States
Elissa Downs
Recruiting
Washington University School of Medicine
St Louis, Missouri, United States
Mark Lowe
Recruiting
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Maisam Abu-El-Haija
Recruiting
Nationwide Children'S Hospital
Columbus, Ohio, United States
Cheryl Gariepy
Recruiting
Children'S Hospital of Philadelphia
Philadelphia, Pennsylvania, United States
Asim Maqbool
Recruiting
Children'S Hospital of Pittsburgh of Upmc
Pittsburgh, Pennsylvania, United States
Douglas Lindblad
Recruiting
University of Texas Southwestern/children'S Medical Center
Dallas, Texas, United States
Megha Mehta
Recruiting
M D Anderson Cancer Center
Houston, Texas, United States
Suresh T. Chari
Recruiting
Texas Children'S Hospital
Houston, Texas, United States
Douglas Fishman
Recruiting
Children'S Hospital of San Antonio
San Antonio, Texas, United States
Adam Noel
Recruiting
Children'S Hospital of Wisconsin
Milwaukee, Wisconsin, United States
Ankur Chugh
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Apr 2021
Primary completion: 2 Feb 2027
Completion: 2 Feb 2027
Last update posted: 4 Mar 2026
Registered enrollment: 1,600
Registry id: NCT06651580

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.