Clinical trialNCT06654037RecruitingPhase 1Interventional

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

SponsorNational Cancer Institute (NCI)Enrollment39Metastatic Microsatellite Stable Colorectal CarcinomaRefractory Microsatellite Stable Colorectal CarcinomaStage IV Colorectal Cancer AJCC v8

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Janie Y Zhang
UPMC Hillman Cancer Center LAO
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Uci Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California, United States
Farshid Dayyani →
Recruiting
Uc Irvine Health/chao Family Comprehensive Cancer Center
Orange, California, United States
Farshid Dayyani →
Recruiting
Montefiore Medical Center - Moses Campus
The Bronx, New York, United States
Chaoyuan Kuang
Recruiting
Montefiore Medical Center-Einstein Campus
The Bronx, New York, United States
Chaoyuan Kuang
Recruiting
Montefiore Medical Center-Weiler Hospital
The Bronx, New York, United States
Chaoyuan Kuang
Recruiting
University of Cincinnati Cancer Center-Uc Medical Center
Cincinnati, Ohio, United States
Davendra P. Sohal
Recruiting
University of Cincinnati Cancer Center-West Chester
West Chester, Ohio, United States
Davendra P. Sohal
Recruiting
University of Pittsburgh Cancer Institute (upci)
Pittsburgh, Pennsylvania, United States
Janie Y. Zhang
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 18 Apr 2025
Primary completion: 1 Apr 2027
Completion: 1 Apr 2027
Last update posted: 13 May 2026
Registered enrollment: 39
Registry id: NCT06654037

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.