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Clinical trialNCT06680232RecruitingPhase 1Interventional

Phase 1 Study to Evaluate Safety and Antiviral Activity of PBGENE-HBV in Adult Patients With Chronic Hepatitis B

SponsorPrecision BioSciences, Inc.Enrollment45HEPATITIS B CHRONIC
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a Phase 1, open-label, dose escalation and dose expansion study to evaluate the safety, tolerability, PK, and antiviral activity of PBGENE-HBV in adult participants with chronic hepatitis B.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

France
  • Hospital Beaujon

    Clichy, France, France

    Recruiting
Hong Kong
  • Queen Mary Hospital, the University of Hong Kong

    Hong Kong, Hong Kong, Hong Kong

    Recruiting
Moldova
  • Ics Arensia Exploratory Medicine Srl

    Chisinau, Moldova

    Recruiting
New Zealand
  • New Zealand Clinical Research

    Auckland, New Zealand

    Recruiting
Romania
  • Arensia Exploratory Medicine

    Bucharest, Romania, Romania

    Recruiting
  • Arensia Exploratory Medicine in Collaboration With County Clinical Emergency Hospital

    Cluj-Napoca, Romania, Romania

    Recruiting
United States
  • Massachusetts General Hospital/harvard University

    Boston, Massachusetts, United States

    Raymond T Chung, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PBGENE-HBV
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
14 Nov 2024
Primary completion
31 Dec 2026
Completion
30 Jun 2027
Last update posted
14 Aug 2026
Registered enrollment
45
Registry id
NCT06680232

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.