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Clinical trialNCT06680921RecruitingPhase 3Interventional

A Study of SIM0270 Combined With Everolimus vs. Treatment of Physician's Choice in Patients With ER+/HER2- Advanced Breast Cancer (SIMRISE)

SponsorJiangsu Simcere Pharmaceutical Co., Ltd.Enrollment460Locally Advanced or Metastatic Breast Cancer
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

60 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

China
  • the First Affiliated Hispital of Bengbu Medical University

    Bengbu, Anhui, China

    Recruiting
  • Anhui Provincial Cancer Hospital

    Hefei, Anhui, China

    Recruiting
  • the First Affiliated Hispital of Anhui Medical University

    Hefei, Anhui, China

    Recruiting
  • Maanshan People'S Hospital

    Maanshan, Anhui, China

    Recruiting
  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, China

    Recruiting
  • the First Medical Center of Pla Ggeneral Hospital

    Beijing, Beijing Municipality, China

    Recruiting
  • the First Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, China

    Recruiting
  • the Second Affiliated Hospital of Chongqing Medical University

    Chongqing, Chongqing Municipality, China

    Recruiting
  • Fujian Cancer Hospital

    Fuzhou, Fujian, China

    Recruiting
  • Fujian Provincial Hospital

    Fuzhou, Fujian, China

    Recruiting
  • the Second Affiliated Hospital of Fujian Medical University

    Quanzhou, Fujian, China

    Not, yet, recruiting
  • Gansu Provincial Cancer Hospital

    Lanzhou, Gansu, China

    Recruiting
  • Guangdong Maternal and Child Health Hospital

    Guangzhou, Guangdong, China

    Recruiting
  • Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University

    Guangzhou, Guangdong, China

    Recruiting
  • Sun Yat-Sen University Cancer Center

    Guangzhou, Guangdong, China

    Recruiting
  • Zhongshan City People'S Hospital

    Zhongshan, Guangdong, China

    Recruiting
  • Guangxi Medical University Cancer Hospital

    Nanning, Guangxi, China

    Recruiting
  • First Hospital of Qinhuangdao

    Qinhuangdao, Hebei, China

    Recruiting
  • the Fourth Hospital of Hebei Medical University

    Shijiazhuang, Hebei, China

    Recruiting
  • Harbin Medical University Cancer Hospital

    Harbin, Heilongjiang, China

    Recruiting
  • Anyang Tumor Hospital

    Anyang, Henan, China

    Recruiting
  • the First Affiliated Hospital of Henan University of Science & Technology

    Luoyang, Henan, China

    Recruiting
  • the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital

    Zhengzhou, Henan, China

    Recruiting
  • the First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, China

    Recruiting
  • Hubei Cancer Hospital

    Wuhan, Hubei, China

    Recruiting
  • Wuhan Central Hospital

    Wuhan, Hubei, China

    Recruiting
  • Wuhan University Zhongnan Hospital

    Wuhan, Hubei, China

    Not, yet, recruiting
  • Xiangyang Central Hospital

    Xiangyang, Hubei, China

    Recruiting
  • the First People'S Hospital of Changde City

    Changde, Hunan, China

    Recruiting
  • Hunan Cancer Hospital

    Changsha, Hunan, China

    Recruiting
  • Xiangya Hospital of Central South University

    Changsha, Hunan, China

    Recruiting
  • the Central Hospital of Yongzhou

    Yongzhou, Hunan, China

    Recruiting
  • Jiangsu Cancer Hospital

    Nanjing, Jiangsu, China

    Recruiting
  • Nanjing Drum Tower Hospital

    Nanjing, Jiangsu, China

    Recruiting
  • the First Affiliated Hospital of Nanjing Medical University

    Nanjing, Jiangsu, China

    Recruiting
  • Xuzhou Central Hospital

    Xuzhou, Jiangsu, China

    Recruiting
  • Jiangxi Cancer Hospital

    Nanchang, Jiangxi, China

    Recruiting
  • Jilin Cancer Hospital

    Changchun, Jilin, China

    Recruiting
  • the First Hospital of Jilin University

    Changchun, Jilin, China

    Recruiting
  • the Second Hospital of Dalian Medical University

    Dalian, Liaoning, China

    Recruiting
20 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
14 Nov 2024
Primary completion
31 Aug 2028
Completion
31 Aug 2028
Last update posted
22 Sept 2025
Registered enrollment
460
Registry id
NCT06680921

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.