Clinical trialNCT06687603RecruitingInterventional

Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

SponsorCase Comprehensive Cancer CenterEnrollment800Barrett EsophagusEsophageal AdenocarcinomaGastroesophageal Reflux

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this clinical trial is to develop a method to detect Barrett's esophagus in individuals with a new office based diagnostic test. Barrett's esophagus is a condition in which the flat pink lining of the swallowing tube that connects the mouth to the stomach (the esophagus) becomes damaged by acid reflux. The main question it aims to answer is: Can this approach demonstrate efficacy for screening of Barrett's esophagus? Participants will: * Participate in a questionnaire. * Undergo a capsule balloon test, called EsoCheck. * Have their EsoCheck sample sent to the laboratory for an EsoGuard test, which is used to detect Barrett's esophagus. * Participants will undergo upper endoscopy as part of standard of care.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Amitabh Chak, MD
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Colorado
Aurora, Colorado, United States
Sachin Wani, MD
Recruiting
Johns Hopkins Hospital
Baltimore, Maryland, United States
Marcia Canto, MD
Recruiting
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States
Nicholas Shaheen, MD
Recruiting
Cleveland Clinic Taussig Cancer Center
Cleveland, Ohio, United States
Prashanti Thota, MD
Recruiting
University Hospitals Cleveland Medical Center
Cleveland, Ohio, United States
Amitabh Chak, MD →
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 10 Mar 2025
Primary completion: 27 Sept 2028
Completion: 27 Sept 2029
Last update posted: 21 Jul 2026
Registered enrollment: 800
Registry id: NCT06687603

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.