Clinical trialNCT06701812RecruitingPhase 2Interventional

Digoxin Medulloblastoma Study

SponsorH. Lee Moffitt Cancer Center and Research InstituteEnrollment23MedulloblastomaMedulloblastoma, Non-WNT/Non-SHH

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Jonathan Metts, MD
Moffitt Cancer Center
Study Chair
clinicaltrials.gov ↗
Laura Metrock, MD
University of Alabama at Birmingham Children's of Alabama
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

15 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham Children'S of Alabama
Birmingham, Alabama, United States
Laura Metrock, MD
Recruiting
Arkansas Childrens Hospital
Little Rock, Arkansas, United States
David Douglass, MD
Recruiting
Connecticut Children'S Medical Center
Hartford, Connecticut, United States
Michael Isakoff, MD
Not, yet, recruiting
Children'S National Medical Center
Washington D.C., District of Columbia, United States
Eugene Hwang, MD
Not, yet, recruiting
Nemours Jacksonville
Jacksonville, Florida, United States
Darren Klawinski, MD
Not, yet, recruiting
University of Miami
Miami, Florida, United States
Bradley Gampel, MD
Not, yet, recruiting
Johns Hopkins All Children'S
St. Petersburg, Florida, United States
Stacie Stapleton, MD
Recruiting
St. Joseph'S Children'S Hospital
Tampa, Florida, United States
Trisha Larkin, MD
Recruiting
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
Baltimore, Maryland, United States
Kenneth Cohen, MD
Recruiting
Washington University St. Louis
St Louis, Missouri, United States
Mohamed Abdelbaki, MD
Recruiting
Montefiore Medical Center
The Bronx, New York, United States
Alice Lee, MD
Recruiting
Unc Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, United States
David Kram, MD
Recruiting
Levine Cancer Institute
Charlotte, North Carolina, United States
Erin Trovillion, MD
Recruiting
Vanderbilt University Medical Center
Nashville, Tennessee, United States
Scott Borinstein, MD
Recruiting
Ut Southwestern
Dallas, Texas, United States
Matthew Campbell, MD
Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Digoxin →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 15 Jan 2026
Primary completion: 28 Feb 2027
Completion: 28 Feb 2027
Last update posted: 7 Jul 2026
Registered enrollment: 23
Registry id: NCT06701812

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.