Clinical trialNCT06738407RecruitingPhase 4Interventional

Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections

SponsorWestatEnrollment760ChlamydiaGonorrheaSexually Transmitted Infections (STIs)Syphilis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this open-label, randomized trial is to assess the efficacy of doxycycline prophylaxis in reducing incidences of bacterial sexually transmitted infections (STIs) among adolescent and young adult females while also evaluating acceptability and antimicrobial resistance in order to inform public health policy.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Cherie Blaire, MD, PhD
University of California, Los Angeles
Study Chair
clinicaltrials.gov ↗
Jenell Stewart, DO, MPH
Hennepin Healthcare
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

13 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Ucla Care
Los Angeles, California, United States
Cherie Blair
Recruiting
San Francisco Department of Public Health
San Francisco, California, United States
Albert Liu
Recruiting
Children'S National Medical Center
Washington D.C., District of Columbia, United States
Natella Rakhmanina
Recruiting
University of Florida
Tampa, Florida, United States
Patricia Emmanuel
Recruiting
Ponce de Leon
Atlanta, Georgia, United States
Anandi Sheth
Recruiting
University Illinois Chicago
Chicago, Illinois, United States
Kelly Bojan
Recruiting
Tulane University
New Orleans, Louisiana, United States
Tina Simpson
Recruiting
Johns Hopkins University
Baltimore, Maryland, United States
Allison Agwu, MD
Recruiting
Harlem Prevention Center
New York, New York, United States
Yael Hirsch-Movermann
Recruiting
Chapel Hill
Chapel Hill, North Carolina, United States
Lina Rosengren-Hovee
Recruiting
Penn Prevention
Philadelphia, Pennsylvania, United States
Arianne Morrison
Not, yet, recruiting
St. Jude Children'S Research Hospital
Memphis, Tennessee, United States
Aditya Gaur
Recruiting
Baylor College of Medicine
Houston, Texas, United States
Mary Paul
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Doxycycline hyclate delayed released 200 mgDoxycycline hyclate delayed released 200 mg weekly

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 27 Feb 2026
Primary completion: 30 Jun 2029
Completion: 30 Jun 2029
Last update posted: 16 Oct 2026
Registered enrollment: 760
Registry id: NCT06738407

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.