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Clinical trialNCT06741085RecruitingPhase 2Interventional

A Study of Stereotactic Radiosurgery (SRS) and Standard Treatment in People With Lung Cancer That Has Spread to the Brain

SponsorMemorial Sloan Kettering Cancer CenterEnrollment56Non Small Cell Lung Cancer Metastatic
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The researchers are doing this study is to find out whether treating brain metastasis with SRS after 3 months of therapy with osimertinib is better than treating with osimertinib alone in people with NSCLC. The researchers will also look at how the study intervention impacts participants' quality of life. The researchers will measure quality of life by having participants complete questionnaires.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Baptist Alliance - Mci (data Collection Only)

    Miami, Florida, United States

    Recruiting
  • Memorial Sloan Kettering Basking Ridge (all Protocol Activities)

    Basking Ridge, New Jersey, United States

    Recruiting
  • Memorial Sloan Kettering Monmouth (all Protocol Activities)

    Middletown, New Jersey, United States

    Recruiting
  • Memorial Sloan Kettering Bergen (all Protocol Activities)

    Montvale, New Jersey, United States

    Recruiting
  • Memorial Sloan Kettering Suffolk - Commack (all Protocol Activities)

    Commack, New York, United States

    Recruiting
  • Memorial Sloan Kettering Westchester (all Protocol Activities)

    Harrison, New York, United States

    Recruiting
  • Memorial Sloan Kettering Cancer Center (all Protocol Activities)

    New York, New York, United States

    Recruiting
  • Memorial Sloan Kettering Nassau (all Protocol Activities)

    Rockville Centre, New York, United States

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Osimertinib →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
13 Dec 2024
Primary completion
31 Dec 2027
Completion
31 Dec 2027
Last update posted
17 Jun 2026
Registered enrollment
56
Registry id
NCT06741085
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.