Clinical trialNCT06783309RecruitingPhase 1/PHASE2Interventional

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

SponsorCOUR Pharmaceutical Development Company, Inc.Enrollment72T1DT1DMT1DM - Type 1 Diabetes MellitusType 1 DiabetesType 1 Diabetes (Juvenile Onset)Type 1 Diabetes Mellitis+4 more conditions

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is a Phase 1b/2a First-in-Human (FIH) clinical trial to assess the safety, tolerability, pharmacodynamics (PD), and efficacy of multiple ascending doses of CNP-103. The approximately 393-days study consists of a Screening Period (28 days), Treatment Period (90 days), and Post-Dose Evaluations (275 days).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Paul Peloso, MD
COUR Pharma
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

38 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Liver Institute Pllc
Tucson, Arizona, United States
Neda Ebrahimi
Recruiting
Wake Research - Tucson
Tucson, Arizona, United States
David Alster
Recruiting
Hoag Memorial Hospital
Newport Beach, California, United States
David Ahn
Recruiting
Rady Children'S Hospital San Diego
San Diego, California, United States
Carla Demeterco-Berggren
Recruiting
Diablo Clinical Research
Walnut Creek, California, United States
Mark Christiansen
Recruiting
Barbara Davis Center for Childhood Diabetes
Aurora, Colorado, United States
Taylor Triolo
Recruiting
Southwest General Healthcare Center
Fort Myers, Florida, United States
Orlando Fernandez
Recruiting
University of Florida
Gainesville, Florida, United States
Timothy Foster
Recruiting
Evolution Research Center
Hialeah, Florida, United States
Andrea Sosa-Melo
Recruiting
Dy Professional Research Center
Miami, Florida, United States
Soroush Aghigh
Recruiting
University of Miami
Miami, Florida, United States
David Baidal
Recruiting
University of South Florida
Tampa, Florida, United States
Henry Rodriguez →
Recruiting
Atlanta Diabetes Association
Atlanta, Georgia, United States
Carson Womack
Recruiting
Children'S Healthcare of Atlanta
Atlanta, Georgia, United States
Kristina Cossen
Recruiting
Emory University
Atlanta, Georgia, United States
Michael Hughes
Recruiting
Rocky Mountain Diabetes and Osteoporosis Center
Idaho Falls, Idaho, United States
Joshua Smith
Recruiting
Northwestern University
Chicago, Illinois, United States
Grazia Aleppo →
Recruiting
Southern Illinois University School of Medicine
Springfield, Illinois, United States
Gabriel Uwaifo
Recruiting
Riley Hospital for Children- Indiana University
Indianapolis, Indiana, United States
Linda DeMeglio
Recruiting
Barry J. Reiner, Md, Llc
Baltimore, Maryland, United States
Barry Reiner
Recruiting
Joslin Diabetes Center
Boston, Massachusetts, United States
Jason Gaglia
Recruiting
Embassy Research Network
Bloomfield Township, Michigan, United States
George Grunberger
Recruiting
University of Minnesota
Minneapolis, Minnesota, United States
Antoinette Moran
Recruiting
Children'S Mercy Hospital
Kansas City, Missouri, United States
Wayne Moore
Recruiting
Washington University School of Medicine
St Louis, Missouri, United States
Janet McGill
Recruiting
Ubmd Pediatrics - University of Buffalo
Buffalo, New York, United States
Lucy Mastrandrea
Recruiting
Nyu Langone Diabetes & Endocrine Associates
New York, New York, United States
Ramachandra Naik
Recruiting
Duke University
Durham, North Carolina, United States
Jennifer Green
Recruiting
Physicians East, Pa
Greenville, North Carolina, United States
Mark Warren →
Recruiting
Wake Research - Raleigh
Raleigh, North Carolina, United States
Khushbu Chandarana
Recruiting
Superior Clinical Research
Smithfield, North Carolina, United States
Clifford Curtis
Recruiting
University Diabetes & Endocrine Consultants
Chattanooga, Tennessee, United States
David Huffman
Recruiting
Texas Diabetes & Endocrinology
Austin, Texas, United States
Jean Chen
Recruiting
M3 Wake Research - Dallas
Dallas, Texas, United States
Carlos Arauz-Pacheco
Recruiting
Accurate Clinical Research, Inc
Humble, Texas, United States
Brian Chou
Recruiting
Diabetes & Glandular Disease (dgd) Clinic, P.A.
San Antonio, Texas, United States
Mark Kipnes →
Recruiting
Topline Clinical, Inc
Waxahachie, Texas, United States
Stephen Mueller
Recruiting
University of Washington Diabetes Institute
Seattle, Washington, United States
Irl Hirsch
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CNP-103Placebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 12 May 2025
Primary completion: 31 Dec 2026
Completion: 30 Jun 2027
Last update posted: 20 Aug 2026
Registered enrollment: 72
Registry id: NCT06783309

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.