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Clinical trialNCT06798012RecruitingPhase 2Interventional

A Study of TAK-411 in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

SponsorTakedaEnrollment36Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

CIDP is an autoimmune disease. This means that the body's germ fighting (immune) system attacks itself. In CIDP, the immune system attacks the protective covering around the nerves called myelin. Over time, these nerves lose their ability to send signals to the muscles in the body. This leads to muscle weakness and loss of sensation in arms and legs among other symptoms. Participants with CIDP can be treated with a protein called immunoglobulin (or IG). TAK-411 is a special type of immune globulin G (hsIgG) that has been chemically changed. It is made from IG that comes from human plasma. This study will test if TAK-411 can decrease inflammation and improve symptoms of CIDP. The main aim of this study is to check how TAK-411 affects the physical functioning of adults with CIDP when compared with results of the placebo group of a historical trial. Participants may be treated with TAK-411 for up to 1 year (51 weeks) and will be followed up for 3 weeks after last dose. During the study, participants may visit their study clinic up to approximately 21 times.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

20 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • University of Calgary

    Calgary, Alberta, Canada

    Christopher White
    Not, yet, recruiting
  • University Health Network

    Toronto, Ontario, Canada

    Vera Bril
    Not, yet, recruiting
Colombia
  • Neuro Clinicas.A.S

    Medellín, Antioquia, Colombia

    Juan Marcos Solano Atehortua
    Not, yet, recruiting
  • Hospital Universitario San Ignacio

    Bogotá, D.C., Colombia

    Alba Lucia Marentes Cubillos
    Not, yet, recruiting
  • Fundacion Valle del Lili

    Cali, Valle del Cauca Department, Colombia

    Francisco Arias Mora
    Not, yet, recruiting
  • Universidad del Rosario

    Bogotá, Colombia

    Andres Diaz Campos
    Not, yet, recruiting
  • Fundacion Oftalmologica de Santander - Foscal

    Bucaramanga, Colombia

    Ivan Peña
    Not, yet, recruiting
United States
  • University of California San Diego

    La Jolla, California, United States

    Dominic Ferrey
    Recruiting
  • California Pacific Medical Center

    San Francisco, California, United States

    Liberty Jenkins
    Recruiting
  • Uf Health Neurology - Jacksonville

    Jacksonville, Florida, United States

    Michael Pulley
    Recruiting
  • Visionary Investigators Network

    Miami, Florida, United States

    Andrew Lerman
    Recruiting
  • University of South Florida

    Tampa, Florida, United States

    Kathleen Murray
    Recruiting
  • Emory University

    Atlanta, Georgia, United States

    Christina Nicole Fournier
    Recruiting
  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, United States

    Fernanda Wajnsztajn Yungher
    Recruiting
  • Mayo Clinic Rochester

    Rochester, Minnesota, United States

    Marcus Pinto
    Recruiting
  • the Curators of the University of Missouri on Behalf of University of Missouri Health Care

    Columbia, Missouri, United States

    William Arnold
    Recruiting
  • the Washington University

    St Louis, Missouri, United States

    Charles Roach
    Recruiting
  • Penn Blood Disorders Program - Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, United States

    Chafic Karam
    Recruiting
  • Houston Methodist Research Institute

    Houston, Texas, United States

    Bing Liao
    Not, yet, recruiting
  • University of Washington

    Seattle, Washington, United States

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

TAK-411
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
14 May 2025
Primary completion
2 Dec 2027
Completion
8 Jun 2028
Last update posted
23 Apr 2026
Registered enrollment
36
Registry id
NCT06798012

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.