Clinical trialNCT06845813CompletedPhase 1Interventional

Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD6234

SponsorAstraZenecaEnrollment24Renal Impairment

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study will evaluate the pharmacokinetics (PK), safety, and tolerability of single subcutaneous dose of AZD6234 with end stage renal disease, severe, and possibly moderate and mild renal impairment in comparison to a matched healthy control group.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Fadi Saba, M.D.
Servico Integrado de Tecnicas Endovasculares
Principal Investigator
clinicaltrials.gov ↗
Joel M Neutel, M.D.
Servico Integrado de Tecnicas Endovasculares
Principal Investigator
clinicaltrials.gov ↗
Kwabena Ayesu, M.D.
Servico Integrado de Tecnicas Endovasculares
Principal Investigator
clinicaltrials.gov ↗
Thomas C Marbury, M.D.
Servico Integrado de Tecnicas Endovasculares
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Research Site
Lake Forest, California, United States
Research Site
Orlando, Florida, United States
Research Site
Orlando, Florida, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AZD6234

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 24 Feb 2025
Primary completion: 30 Sept 2025
Completion: 30 Sept 2025
Last update posted: 3 Nov 2025
Registered enrollment: 24
Registry id: NCT06845813

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.