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Clinical trialNCT06863311RecruitingPhase 2Interventional

Trial of Zanzalintinib (XL092) in Combination With Immunotherapy in Patients Who Progress on Adjuvant Therapy in Clear Cell RCC

SponsorKarie RuncieEnrollment70Advanced Renal Cell CarcinomaClear Cell Renal Cell CarcinomaMetastatic Renal Cell Carcinoma
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of California San Diego

    La Jolla, California, United States

    Rana McKay, MD
    Recruiting
  • Indiana University Melvin and Bren Simon Comprehensive Cancer Center

    Indianapolis, Indiana, United States

    Jennifer King, MD
    Recruiting
  • Washington University School of Medicine

    St Louis, Missouri, United States

    Melissa Reimers, MD
    Recruiting
  • Columbia University Irving Medical Center

    New York, New York, United States

    Karie Runcie, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

NivolumabZanzalintinib
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
13 Mar 2026
Primary completion
31 Dec 2027
Completion
31 Dec 2028
Last update posted
18 May 2026
Registered enrollment
70
Registry id
NCT06863311

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.