Clinical trialNCT06876363RecruitingPhase 1/PHASE2Interventional

Study of EN-374 Gene Therapy in Participants With X-Linked Chronic Granulomatous Disease

SponsorEnsomaEnrollment15X-Linked Chronic Granulomatous Disease

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United Kingdom

University College London Hospital
London, United Kingdom
Emma Morris, MB BChir, PhD
Recruiting

United States

University of California, Los Angeles
Los Angeles, California, United States
Donald Kohn, MDGary Schiller, MD
Recruiting
University of California, San Francisco
San Francisco, California, United States
Morna Dorsey, MD, MS
Recruiting
Johns Hopkins All Children'S Hospital
St. Petersburg, Florida, United States
Jennifer Leiding, MD
Recruiting
Boston Children'S Hospital
Boston, Massachusetts, United States
Susan Prockop, MD
Recruiting
University of Minnesota
Minneapolis, Minnesota, United States
Christen Ebens, MD, MPH
Recruiting
Columbia University Irving Medical Center, Morgan Stanley Children'S Hospital
New York, New York, United States
Joseph Oved, MD
Recruiting
Duke University
Durham, North Carolina, United States
Kris Mahadeo, MD, MPHTalal Mousallem, MD
Recruiting
University of Utah, Primary Children'S Hospital
Salt Lake City, Utah, United States
Ahmad Rayes, MD, MSc
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 5 Aug 2025
Primary completion: 31 Dec 2027
Completion: 31 Dec 2027
Last update posted: 27 Apr 2026
Registered enrollment: 15
Registry id: NCT06876363

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.