Clinical trialNCT06961864RecruitingInterventional

Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli

SponsorUniversity of MinnesotaEnrollment100HealthyMigraineVisual Snow Syndrome

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: * Does VSS arise from spontaneous activity in brain pathways? * Where in the brain does the activity contributing to VSS arise? * How does brain activity contribute to VSS? Participants will: 1. Undergo assessments and questionnaires to understand visual and mental symptoms, cognitive, and sensory function. 2. Make visual judgements based on images presented to them both inside and outside a magnetic resonance imaging (MRI) machine. 3. Undergo scanning of their brain while inside of an MRI machine.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Abby Metzler, M.D.
University of Minnesota, Department of Neurology
Study Chair
clinicaltrials.gov ↗
Carrie E Robertson, M.D.
Mayo Clinic, Rochester, Department of Neurology
Study Chair
clinicaltrials.gov ↗
Malgorzata Marjanska, Ph.D.
University of Minnesota, Department of Radiology
Study Chair
clinicaltrials.gov ↗
Michael S Lee, M.D.
University of Minnesota, Department of Ophthalmology and Visual Neurosciences
Study Chair
clinicaltrials.gov ↗
Michael-Paul Schallmo, Ph.D.
University of Minnesota, Department of Psychiatry and Behavioral Sciences
Principal Investigator
clinicaltrials.gov ↗
Stephen A Engel, Ph.D.
University of Minnesota, Department of Psychology
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Minnesota
Minneapolis, Minnesota, United States
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 11 Apr 2025
Primary completion: 31 Mar 2030
Completion: 31 Mar 2030
Last update posted: 14 Jan 2026
Registered enrollment: 100
Registry id: NCT06961864

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.