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Clinical trialNCT06982820RecruitingInterventional

Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With Anhedonia

SponsorGrayMatters Health Ltd.Enrollment170Depressive Disorder, Major
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this research is to learn more about a new treatment for individuals with Major Depressive Disorder (MDD) with heightened symptoms of anhedonia (i.e. loss of pleasure or interest in activities). The treatment is called Prism, and it is a software device intended for a novel form of neurofeedback training to be used in a clinic setting. During this study, the subject will use different techniques to measure brain activities, including magnetic resonance imaging (MRI) and electroencephalography (EEG).
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Israel
  • Sheba Medical Center

    Ramat Gan, Israel

    Raz Gross, MD
    Recruiting
United States
  • Butler Hospital

    Providence, Rhode Island, United States

    Linda Carpenter, MD
    Recruiting
  • Houston Center for Advanced Psychiatric Treatment

    Houston, Texas, United States

    Sandhya Prashad, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
25 Jun 2025
Primary completion
30 May 2027
Completion
30 Aug 2027
Last update posted
1 May 2026
Registered enrollment
170
Registry id
NCT06982820
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.