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Clinical trialNCT06991556RecruitingPhase 2Interventional

An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

SponsorNovartis PharmaceuticalsEnrollment150Metastatic Hormone-sensitive Prostate Cancer
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

67 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Novartis Investigative Site

    Adelaide, South Australia, Australia

    Recruiting
  • Novartis Investigative Site

    Clayton, Victoria, Australia

    Recruiting
Brazil
  • Novartis Investigative Site

    Fortaleza, Ceará, Brazil

    Recruiting
  • Novartis Investigative Site

    São Paulo, São Paulo, Brazil

    Recruiting
Canada
  • Novartis Investigative Site

    Vancouver, British Columbia, Canada

    Recruiting
  • Novartis Investigative Site

    Halifax, Nova Scotia, Canada

    Recruiting
  • Novartis Investigative Site

    Montreal, Quebec, Canada

    Recruiting
China
  • Novartis Investigative Site

    Beijing, Chaoyang, China

    Recruiting
  • Novartis Investigative Site

    Beijing, China

    Recruiting
Czechia
  • Novartis Investigative Site

    Brno, Czechia

    Recruiting
  • Novartis Investigative Site

    Olomouc, Czechia

    Recruiting
  • Novartis Investigative Site

    Prague, Czechia

    Recruiting
France
  • Novartis Investigative Site

    Nice, Alpes Maritimes, France

    Recruiting
  • Novartis Investigative Site

    Marseille, France

    Recruiting
  • Novartis Investigative Site

    Quint-Fonsegrives, France

    Recruiting
  • Novartis Investigative Site

    Suresnes, France

    Recruiting
Germany
  • Novartis Investigative Site

    Düsseldorf, North Rhine-Westphalia, Germany

    Recruiting
  • Novartis Investigative Site

    Hamburg, Germany

    Recruiting
  • Novartis Investigative Site

    Lübeck, Germany

    Recruiting
  • Novartis Investigative Site

    Nürtingen, Germany

    Recruiting
Italy
  • Novartis Investigative Site

    Asti, AT, Italy

    Recruiting
  • Novartis Investigative Site

    Padova, PD, Italy

    Recruiting
  • Novartis Investigative Site

    Trento, TN, Italy

    Recruiting
  • Novartis Investigative Site

    Orbassano, TO, Italy

    Recruiting
  • Novartis Investigative Site

    Verona, VR, Italy

    Recruiting
Netherlands
  • Novartis Investigative Site

    Zwolle, Overijssel, Netherlands

    Recruiting
  • Novartis Investigative Site

    Dordrecht, South Holland, Netherlands

    Recruiting
  • Novartis Investigative Site

    Hoofddorp, Netherlands

    Recruiting
  • Novartis Investigative Site

    Schiedam, Netherlands

    Recruiting
Poland
  • Novartis Investigative Site

    Kielce, Poland

    Recruiting
  • Novartis Investigative Site

    Olsztyn, Poland

    Recruiting
  • Novartis Investigative Site

    Oświęcim, Poland

    Recruiting
  • Novartis Investigative Site

    Skorzewo, Poland

    Recruiting
Singapore
  • Novartis Investigative Site

    Singapore, Singapore

    Recruiting
  • Novartis Investigative Site

    Singapore, Singapore

    Recruiting
  • Novartis Investigative Site

    Singapore, Singapore

    Recruiting
South Korea
  • Novartis Investigative Site

    Seoul, South Korea

    Recruiting
  • Novartis Investigative Site

    Seoul, South Korea

    Recruiting
Spain
  • Novartis Investigative Site

    Santander, Cantabria, Spain

    Recruiting
  • Novartis Investigative Site

    Badajoz, Extremadura, Spain

    Recruiting
27 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
7 Jul 2025
Primary completion
29 Mar 2032
Completion
19 Oct 2035
Last update posted
10 Jun 2026
Registered enrollment
150
Registry id
NCT06991556

Cross-registrations

EU-CTR / CTIS (EudraCT)2024-520156-22-00

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.