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Clinical trialNCT07001384RecruitingPhase 1Interventional

A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL)

SponsorMemorial Sloan Kettering Cancer CenterEnrollment30Anaplastic Large Cell LymphomaAnaplastic Lymphoma Kinase
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The researchers are doing this study to see if alectinib in combination with duvelisib is a safe and effective time-limited treatment for people with relapsed or refractory ALK+ anaplastic large cell lymphoma (ALCL). The researchers will test different doses of the study drugs to find the highest doses that cause few or mild side effects in participants. Once they find this dose combination, they will test it in a new group of participants to learn how long the effect of the combination lasts after the end of treatment
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Memorial Sloan Kettering Basking Ridge (limitedprotocol Activities)

    Basking Ridge, New Jersey, United States

    Recruiting
  • Memorial Sloan Kettering Monmouth (limited Protocol Activities)

    Middletown, New Jersey, United States

    Recruiting
  • Memorial Sloan Kettering Bergen (limited Protocol Activities)

    Montvale, New Jersey, United States

    Recruiting
  • Memorial Sloan Kettering Suffolk - Commack (limited Protocol Activities)

    Commack, New York, United States

    Recruiting
  • Memorial Sloan Kettering Westchester (limited Protocol Activities)

    Harrison, New York, United States

    Recruiting
  • Memorial Sloan Kettering Cancer Center (all Protocol Activities)

    New York, New York, United States

    Recruiting
  • Memorial Sloan Kettering Nassau (limited Protocol Activities)

    Uniondale, New York, United States

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Alectinib →Duvelisib →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
8 Aug 2025
Primary completion
8 Aug 2031
Completion
8 Aug 2031
Last update posted
26 May 2026
Registered enrollment
30
Registry id
NCT07001384
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.