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Clinical trialNCT07003100RecruitingObservational

A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

SponsorCity of Hope Medical CenterEnrollment100Recurrent Mycosis FungoidesRecurrent Sezary SyndromeRefractory Mycosis FungoidesRefractory Sezary SyndromeStage IB Mycosis Fungoides and Sezary Syndrome AJCC v8Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v8+3 more conditions
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is being done to assess mogamulizumab-associated rash in patients diagnosed with mycosis fungoides or sezary syndrome and treated with standard of care mogamulizumab. One of the most common side effects of mogamulizumab is a rash, currently named mogamulizumab-associated rash (MAR) which can look like MF or SS. However, mogamulizumab-associated rash (MAR) does not indicate failure of mogamulizumab, and may be a sign that the drug is working. If not properly evaluated, mogamulizumab-associated rash (MAR) could be misinterpreted as worsening of mycosis fungoides/sezary syndrome, which could lead doctors to recommend stopping mogamulizumab treatment early. The information learned by doing this research study may help tell the difference between mogamulizumab-associated rash (MAR) (sometimes also called "drug eruption") and worsening of the disease. It may also help to uncover information about the cause of mogamulizumab-associated rash (MAR).

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • City of Hope Medical Center

    Duarte, California, United States

    Christiane Querfeld
    Recruiting
  • Stanford Cancer Institute Palo Alto

    Palo Alto, California, United States

    Youn H. Kim
    Not, yet, recruiting
  • Moffitt Cancer Center

    Tampa, Florida, United States

    Pei-Ling Chen
    Not, yet, recruiting
  • Emory University Hospital/winship Cancer Institute

    Atlanta, Georgia, United States

    Pamela B. Allen
    Not, yet, recruiting
  • Johns Hopkins University/sidney Kimmel Cancer Center

    Baltimore, Maryland, United States

    Sima Rozati
    Not, yet, recruiting
  • Brigham and Women'S Hospital

    Boston, Massachusetts, United States

    Cecilia A. Larocca
    Not, yet, recruiting
  • Siteman Cancer Center at Washington University

    St Louis, Missouri, United States

    Neha Mehta Shah
    Recruiting
  • Thomas Jefferson University Hospital

    Philadelphia, Pennsylvania, United States

    Neda Nikbakht
    Not, yet, recruiting
  • M D Anderson Cancer Center

    Houston, Texas, United States

    Auris Huen
    Not, yet, recruiting
  • Fred Hutchinson Cancer Center

    Seattle, Washington, United States

    Michi M. Shinohara
    Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
6 Dec 2024
Primary completion
19 Oct 2026
Completion
19 Oct 2026
Last update posted
9 Sept 2025
Registered enrollment
100
Registry id
NCT07003100

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.