Clinical trialNCT07006675RecruitingPhase 3Interventional

Effect of NSAIDs on Union, Opioid Utilization and Pain Management for Tibia Fractures: A Pragmatic, Randomized Controlled Trial

SponsorMajor Extremity Trauma Research ConsortiumEnrollment1,000PainTibial Fractures

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Renan Castillo, PhD
Johns Hopkins University
Principal Investigator
clinicaltrials.gov ↗
Thomas Higgins, MD
University of Utah
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

14 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

University of Calgary, Foothills Medical Centre
Calgary, Alberta, Canada
Prism Schneider, MD
Recruiting

United States

Eskenazi Hospital
Indianapolis, Indiana, United States
Karl Shively, MD
Recruiting
Indiana University-Methodist
Indianapolis, Indiana, United States
Brian Mullis, MD
Recruiting
University of Maryland R Adams Cowley Shock Trauma Center
Baltimore, Maryland, United States
Robert O'Toole, MD
Recruiting
Harvard Medical Center
Cambridge, Massachusetts, United States
Michael Weaver, MD
Recruiting
Hennepin Health
Minneapolis, Minnesota, United States
Andrew Schmidt, MDNancy Luger, MD
Recruiting
University of Mississippi
Jackson, Mississippi, United States
Patrick Bergin, MD
Recruiting
the Metrohealth System
Cleveland, Ohio, United States
Nicholas Romeo, MD
Recruiting
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States
Gregory Altman, MD
Recruiting
Vanderbilt Medical Center
Nashville, Tennessee, United States
William Obremskey, MD
Recruiting
University of Texas Health Science Center - Houston
Houston, Texas, United States
Stephen Warner, MD
Recruiting
University of Utah
Salt Lake City, Utah, United States
Thomas Higgins, MD
Recruiting
Inova Fairfax Hospital
Falls Church, Virginia, United States
Greg Gaski, MD
Recruiting
University of Wisconsin
Madison, Wisconsin, United States
Chris Domes, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 26 May 2021
Primary completion: 31 Dec 2026
Completion: 31 Mar 2027
Last update posted: 5 Jun 2025
Registered enrollment: 1,000
Registry id: NCT07006675

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.