Clinical trialNCT07061977RecruitingPhase 3Interventional

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

SponsorNational Cancer Institute (NCI)Enrollment336Locally Advanced Cervical AdenocarcinomaLocally Advanced Cervical Adenosquamous CarcinomaLocally Advanced Cervical Squamous Cell CarcinomaStage IIIA Cervical Cancer FIGO 2018Stage IIIB Cervical Cancer FIGO 2018Stage IIIC1 Cervical Cancer FIGO 2018+2 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jyoti S Mayadev
NRG Oncology
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

294 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States
Charles A. Leath
Not, yet, recruiting
Highlands Oncology Group - Fayetteville
Fayetteville, Arkansas, United States
Joseph T. Beck
Recruiting
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States
Heather R. Williams
Recruiting
Highlands Oncology Group - Rogers
Rogers, Arkansas, United States
Joseph T. Beck
Recruiting
Highlands Oncology Group
Springdale, Arkansas, United States
Joseph T. Beck
Recruiting
Kaiser Permanente-Bellflower
Bellflower, California, United States
Devansu Tewari
Recruiting
City of Hope Corona
Corona, California, United States
Scott M. Glaser
Recruiting
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Scott M. Glaser
Recruiting
Kaiser Permanente South Bay
Harbor City, California, United States
Devansu Tewari
Recruiting
City of Hope at Irvine Lennar
Irvine, California, United States
Scott M. Glaser
Recruiting
Kaiser Permanente-Irvine
Irvine, California, United States
Devansu Tewari
Recruiting
Uci Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California, United States
Erin H. Healy
Recruiting
Uc San Diego Moores Cancer Center
La Jolla, California, United States
Jyoti S. Mayadev
Recruiting
City of Hope Antelope Valley
Lancaster, California, United States
Suspended
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States
Devansu Tewari
Recruiting
Kaiser Permanente West Los Angeles
Los Angeles, California, United States
Devansu Tewari
Recruiting
Uc Irvine Health/chao Family Comprehensive Cancer Center
Orange, California, United States
Erin H. Healy
Recruiting
Kaiser Permanente - Panorama City
Panorama City, California, United States
Devansu Tewari
Recruiting
Kaiser Permanente-San Diego Zion
San Diego, California, United States
Devansu Tewari
Recruiting
Kaiser Permanente-San Marcos
San Marcos, California, United States
Devansu Tewari
Recruiting
City of Hope South Pasadena
South Pasadena, California, United States
Scott M. Glaser
Recruiting
City of Hope Upland
Upland, California, United States
Scott M. Glaser
Recruiting
Kaiser Permanente-Woodland Hills
Woodland Hills, California, United States
Devansu Tewari
Recruiting
Uchealth University of Colorado Hospital
Aurora, Colorado, United States
Spyridon A. Mastroyannis
Recruiting
Uchealth Highlands Ranch Hospital
Highlands Ranch, Colorado, United States
Spyridon A. Mastroyannis
Recruiting
Danbury Hospital
Danbury, Connecticut, United States
Leslie Andriani
Recruiting
Norwalk Hospital
Norwalk, Connecticut, United States
Leslie Andriani
Recruiting
Beebe South Coastal Health Campus
Millville, Delaware, United States
Gregory A. Masters
Recruiting
Helen F Graham Cancer Center
Newark, Delaware, United States
Gregory A. Masters
Recruiting
Medical Oncology Hematology Consultants Pa
Newark, Delaware, United States
Gregory A. Masters
Recruiting
Beebe Health Campus
Rehoboth Beach, Delaware, United States
Gregory A. Masters
Recruiting
Um Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, United States
Navya Nair
Recruiting
Um Sylvester Comprehensive Cancer Center at Coral Springs
Coral Springs, Florida, United States
Navya Nair
Recruiting
Um Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, United States
Navya Nair
Recruiting
Um Sylvester Comprehensive Cancer Center at Doral
Doral, Florida, United States
Navya Nair
Recruiting
Broward Health Medical Center
Fort Lauderdale, Florida, United States
Scott E. Jordan
Recruiting
Memorial Regional Hospital/joe Dimaggio Children'S Hospital
Hollywood, Florida, United States
Tamara L. Smith
Recruiting
Um Sylvester Comprehensive Cancer Center at Hollywood
Hollywood, Florida, United States
Navya Nair
Recruiting
Um Sylvester Comprehensive Cancer Center at Kendall
Miami, Florida, United States
Navya Nair
Recruiting
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, United States
Navya Nair
Recruiting

254 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 5 Nov 2025
Primary completion: 31 Dec 2030
Completion: 31 Dec 2030
Last update posted: 10 Jul 2026
Registered enrollment: 336
Registry id: NCT07061977

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.