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Clinical trialNCT07062848Active, not recruitingObservational

An Observational Study Using Artificial Intelligence (AI) Algorithms on Electrocardiography (ECG), Point-of-care Ultrasound (POCUS), and Transthoracic Echocardiophy (TTE) to Estimate the Under-diagnosis of Transthyretin Amyloid Cardiomyopathy (ATTR-CM) Across a Diverse Range of US Health Systems.

SponsorYale UniversityEnrollment1,500,000Transthyretin (TTR) Amyloid Cardiomyopathy
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a multi-center, observational study with the overall objective to examine the scale of under-diagnosis for transthyretin amyloid cardiomyopathy (ATTR-CM) across a broad range of diverse health systems in the US using a fully federated deployment of an artificial intelligence (AI) toolkit of algorithms that detect ATTR-CM on electrocardiography (ECG), point-of-care ultrasound (POCUS), and transthoracic echocardiography (TTE).
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

12 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of California - San Francisco (ucsf) Health

    San Francisco, California, United States

  • Yale New Haven Health System

    New Haven, Connecticut, United States

  • the University of Chicago

    Chicago, Illinois, United States

  • Henry Ford Health

    Detroit, Michigan, United States

  • Mount Sinai

    New York, New York, United States

  • Montefiore

    The Bronx, New York, United States

  • Providence Health

    Tigard, Oregon, United States

  • Medical University of South Carolina (musc) Health

    Charleston, South Carolina, United States

  • Ut Southwestern Medical Center

    Dallas, Texas, United States

  • Houstin Methodist

    Houston, Texas, United States

  • University of Virginia School of Medicine

    Charlottesville, Virginia, United States

  • University of Washington Medicine

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
24 Jan 2025
Primary completion
31 Jan 2027
Completion
31 Jan 2027
Last update posted
29 Jul 2026
Registered enrollment
1,500,000
Registry id
NCT07062848
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.