Clinical trialNCT07120503Active, not recruitingPhase 2Interventional

Study to Evaluate the Safety, Pharmacology and Efficacy of WIN378 in Adults With Moderate or Severe Asthma

SponsorWindward BioEnrollment136Asthma (Diagnosis)

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is trying to identify the right dose of a long-acting medicine called WIN378 for people with moderate or severe asthma. WIN378 blocks the action of a protein called TSLP which causes inflammation in the lung and may contribute to your asthma control and symptoms. The study will test how doses of WIN378 are handled by your body (pharmacokinetics) and assess the safety of the medicine and will assess markers of asthma inflammation in your breath and in your blood, lung function and asthma control (pharmacodynamics).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Omar Khwaja, MD
Windward Bio
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

73 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Argentina

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Buenos Aires, Buenos Aires F.D., Argentina
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Buenos Aires, Buenos Aires F.D., Argentina
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Buenos Aires, Buenos Aires F.D., Argentina
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Buenos Aires, Buenos Aires F.D., Argentina
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Buenos Aires, Buenos Aires F.D., Argentina
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Buenos Aires, Buenos Aires F.D., Argentina
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Córdoba, Córdoba Province, Argentina
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Paraná, Entre Ríos Province, Argentina
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Rosario, Santa Fe Province, Argentina
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Rosario, Santa Fe Province, Argentina
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Santa Fe, Santa Fe Province, Argentina
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San Miguel de Tucumán, Tucumán Province, Argentina
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San Miguel de Tucumán, Tucumán Province, Argentina
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San Miguel de Tucumán, Tucumán Province, Argentina

Australia

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Brookvale, New South Wales, Australia
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Coffs Harbour, New South Wales, Australia
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Maroubra, New South Wales, Australia
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Miranda, New South Wales, Australia
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Wollongong, New South Wales, Australia
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Birtinya, Queensland, Australia
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North Altona, Victoria, Australia

Bulgaria

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Sofia, Grad Sofia, Bulgaria
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Lovech, Lovech, Bulgaria
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Rousse, Ruse, Bulgaria
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Sofia, Sofia, Bulgaria
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Sofia, Sofia, Bulgaria

France

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Pessac, Bordeaux, France
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Dijon, Côte-dOr, France
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Montpellier, Hérault, France
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La Tronche, Isère, France
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Nantes, Loire-Atlantique, France

Germany

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Berlin, Loire-Atlantique, Germany
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München, Loire-Atlantique, Germany
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Bendorf, Rhineland-Palatinate, Germany
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Lübeck, Schleswig-Holstein, Germany
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Darmstadt, Germany
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Frankfurt am Main, Germany
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Frankfurt am Main, Germany
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Leipzig, Germany
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Mainz, Germany

33 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboWIN378

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 24 Jul 2025
Primary completion: 31 Jul 2027
Completion: 31 Oct 2027
Last update posted: 7 Apr 2026
Registered enrollment: 136
Registry id: NCT07120503

Cross-registrations

EU-CTR / CTIS (EudraCT)2025-521391-58-00

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.