FindMyKOL
Clinical trialNCT07172204RecruitingPhase 2Interventional

Alternating Regimen of VA and Low-dose CHA in the Treatment of Unfit Newly Diagnosed AML

SponsorFirst Affiliated Hospital of Zhejiang UniversityEnrollment25Age ≥60Intensive Chemotherapy UnfitNewly Diagnosed Acute Myeloid Leukemia (AML)
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This phase II trial tests how well VA alternating with low-dose CHA works in treating unfit patients with newly diagnosed acute myeloid leukemia (AML). This is a prospective, multi-centers, single arm phase II study aimed to overcome VEN resistance and achieve greater MRD negative rate, providing better control of treatment for unfit AML.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

  • Jie Dr. Sun, M.D, Ph.D

    Bone Marrow Transplantation Center of The First Affiliated Hospital, Zhejiang University School of Medicine

    Principal Investigator
    clinicaltrials.gov ↗
  • Shanshan Prof. Pei, Ph.D

    Liangzhu Laboratory, Zhejiang University School of Medicine

    Study Director
    clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

China
  • Beijing Chao-Yang Hospital, Capital Medical University

    Beijing, Beijing Municipality, China

    Recruiting
  • Shenzhen University General Hospital

    Shenzhen, Guangdong, China

    Recruiting
  • the First Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, China

    Recruiting
  • the Second Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, China

    Recruiting
  • Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Alternately treated with VA/low CHA regimen
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
16 Sept 2025
Primary completion
31 Jul 2027
Completion
31 Jul 2029
Last update posted
4 Feb 2026
Registered enrollment
25
Registry id
NCT07172204
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.