Clinical trialNCT07215910RecruitingPhase 3Interventional

Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

SponsorAlliance for Clinical Trials in OncologyEnrollment408Astrocytoma, IDH-Mutant, Grade 3

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Patrick Y Wen, MD
Alliance for Clinical Trials in Oncology
Study ChairKOL profile →
clinicaltrials.gov ↗
Rifaquat M. Rahman, MD
Alliance for Clinical Trials in Oncology
Study Chair
clinicaltrials.gov ↗
Ugonma N Chukwueke, MD
Alliance for Clinical Trials in Oncology
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

82 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

City of Hope Comprehensive Cancer Center
Duarte, California, United States
Keng Lam
Recruiting
Uci Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California, United States
Xiao-Tang Kong
Recruiting
Uc Irvine Health/chao Family Comprehensive Cancer Center
Orange, California, United States
Xiao-Tang Kong
Recruiting
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States
Orwa Aboud
Recruiting
Yale University
New Haven, Connecticut, United States
Daniela R. Galluzzo
Recruiting
Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut, United States
Daniela R. Galluzzo
Recruiting
Smilow Cancer Hospital Care Center - Waterford
Waterford, Connecticut, United States
Daniela R. Galluzzo
Recruiting
Helen F Graham Cancer Center
Newark, Delaware, United States
Gregory A. Masters
Recruiting
Medical Oncology Hematology Consultants Pa
Newark, Delaware, United States
Gregory A. Masters
Recruiting
Illinois Cancercare-Bloomington
Bloomington, Illinois, United States
Bryan A. Faller
Recruiting
Osf Saint Joseph Medical Center
Bloomington, Illinois, United States
Bryan A. Faller
Recruiting
Illinois Cancercare-Canton
Canton, Illinois, United States
Bryan A. Faller
Recruiting
Illinois Cancercare-Carthage
Carthage, Illinois, United States
Bryan A. Faller
Recruiting
University of Illinois
Chicago, Illinois, United States
Stefania Maraka
Recruiting
Illinois Cancercare-Eureka
Eureka, Illinois, United States
Bryan A. Faller
Recruiting
Northshore University Healthsystem-Evanston Hospital
Evanston, Illinois, United States
Christopher R. Trevino
Recruiting
Illinois Cancercare-Galesburg
Galesburg, Illinois, United States
Bryan A. Faller
Recruiting
Northshore University Healthsystem-Glenbrook Hospital
Glenview, Illinois, United States
Christopher R. Trevino
Recruiting
Northshore University Healthsystem-Highland Park Hospital
Highland Park, Illinois, United States
Christopher R. Trevino
Recruiting
Illinois Cancercare-Kewanee Clinic
Kewanee, Illinois, United States
Bryan A. Faller
Recruiting
Illinois Cancercare-Macomb
Macomb, Illinois, United States
Bryan A. Faller
Recruiting
Illinois Cancercare-Ottawa Clinic
Ottawa, Illinois, United States
Bryan A. Faller
Recruiting
Illinois Cancercare-Pekin
Pekin, Illinois, United States
Bryan A. Faller
Recruiting
Illinois Cancercare-Peoria
Peoria, Illinois, United States
Bryan A. Faller
Recruiting
Osf Saint Francis Medical Center
Peoria, Illinois, United States
Bryan A. Faller
Recruiting
Osf Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria, Illinois, United States
Bryan A. Faller
Recruiting
Illinois Cancercare-Peru
Peru, Illinois, United States
Bryan A. Faller
Recruiting
Illinois Cancercare-Princeton
Princeton, Illinois, United States
Bryan A. Faller
Recruiting
Illinois Cancercare - Washington
Washington, Illinois, United States
Bryan A. Faller
Recruiting
Midwestern Regional Medical Center
Zion, Illinois, United States
Laura Farrington
Recruiting
Ui Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny, Iowa, United States
Seema Harichand-Herdt
Recruiting
Ui Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive, Iowa, United States
Seema Harichand-Herdt
Recruiting
Broadlawns Medical Center
Des Moines, Iowa, United States
Seema Harichand-Herdt
Recruiting
Iowa Methodist Medical Center
Des Moines, Iowa, United States
Seema Harichand-Herdt
Recruiting
Mercy Medical Center - Des Moines
Des Moines, Iowa, United States
Richard L. Deming
Recruiting
Ui Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines, Iowa, United States
Seema Harichand-Herdt
Recruiting
Ui Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines, Iowa, United States
Seema Harichand-Herdt
Recruiting
Ui Healthcare Mission Cancer and Blood - Pella
Pella, Iowa, United States
Seema Harichand-Herdt
Recruiting
Ui Health Care Mission Cancer and Blood - Waukee Clinic
Waukee, Iowa, United States
Seema Harichand-Herdt
Recruiting
West Jefferson Medical Center
Marrero, Louisiana, United States
Yazmin Odia
Recruiting

42 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Placebo AdministrationTemozolomide →Vorasidenib →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 20 Jul 2026
Primary completion: 31 May 2033
Completion: 31 Jan 2040
Last update posted: 2 Jul 2026
Registered enrollment: 408
Registry id: NCT07215910

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.