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Clinical trialNCT07219407RecruitingPhase 2Interventional

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

SponsorRapport Therapeutics Inc.Enrollment30EpilepsyFocal EpilepsyFocal Onset SeizureFocal SeizureRefractory Focal EpilepsySeizure
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a clinical research study for an investigational drug called RAP-219 in patients with Refractory Focal Epilepsy. This study is being conducted to determine RAP-219 Long- term safety and open-label antiseizure activity in patients with Refractory Focal Epilepsy.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Consultants in Epilepsy and Neurology, Pllc

    Boise, Idaho, United States

    Recruiting
  • Mayo Clinic

    Rochester, Minnesota, United States

    Recruiting
  • Nyu Langone Comprehensive Epilepsy Center

    New York, New York, United States

    Recruiting
  • Cleveland Clinic Foundation

    Cleveland, Ohio, United States

    Recruiting
  • University of Pennsylvania - Department of Neurology

    Philadelphia, Pennsylvania, United States

    Recruiting
  • Vanderbilt University Medical Center

    Nashville, Tennessee, United States

    Recruiting
  • Baylor College of Medicine

    Houston, Texas, United States

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

RAP-219
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
15 Dec 2025
Primary completion
3 Feb 2028
Completion
3 Feb 2028
Last update posted
23 Jan 2026
Registered enrollment
30
Registry id
NCT07219407

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.