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Clinical trialNCT07222462RecruitingInterventional

A Superiority Trial of Radiofrequency Ablation for Low Back Pain

SponsorUniversity of WashingtonEnrollment300Chronic Low Back Pain (CLBP)
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of the ASTRAL Study is to evaluate the effectiveness of LRFA (Lumbar radiofrequency ablation) against a control procedure. The ASTRAL Study will enroll individuals with chronic low back pain (CLBP) and randomly assign them to one of three groups: lumbar radiofrequency ablation using conventional electrodes placed parallel to the medial branch nerves (LRFA-C), lumbar radiofrequency ablation using multi-tined electrodes placed perpendicular to the medial branch nerves (LRFA-M), or a simulated radiofrequency ablation procedure.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Emory Musculoskeletal Institute

    Atlanta, Georgia, United States

    Mikhail Zhukalin, DO
    Recruiting
  • Cleveland Clinic

    Cleveland, Ohio, United States

    Alison Stout, DO
    Recruiting
  • University of Utah Orthopaedic Center/pm&r

    Salt Lake City, Utah, United States

    Zachary McCormick, MD
    Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
4 Feb 2026
Primary completion
31 Mar 2029
Completion
31 Aug 2029
Last update posted
9 Feb 2026
Registered enrollment
300
Registry id
NCT07222462
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.